Structured evidence table for Prebiotics Constipation Meta-Analysis, generated from 2 reusable source documents in the Migaku knowledge base.
| topic | claim | evidence level | citation | source |
|---|---|---|---|---|
| Prebiotics Constipation Meta-Analysis | 1 2 3 4 5 5 6 7 6 7 Irritable bowel syndrome (IBS) is a chronic disorder of gut–brain interaction characterized by recurrent abdominal pain associated with altered bowel habits, in the absence of identifiable structural abnormalities []. | 3 | Šuran Jelena (2026) | IBS and SIBO: Gut Microbiota, Pathophysiology, and Non-Pharmacological Interventions |
| Prebiotics Constipation Meta-Analysis | Early studies reported SIBO in up to 60–78% of IBS cases based on lactulose breath testing [,,], though later investigations using more rigorous methods found lower prevalences (e.g., 4–20%) [,]. | 3 | Šuran Jelena (2026) | IBS and SIBO: Gut Microbiota, Pathophysiology, and Non-Pharmacological Interventions |
| Prebiotics Constipation Meta-Analysis | Moreover, increasing evidence implicating the gut microbiota in IBS/SIBO has spurred interest in interventions that modulate microbial communities. | 3 | Šuran Jelena (2026) | IBS and SIBO: Gut Microbiota, Pathophysiology, and Non-Pharmacological Interventions |
| Prebiotics Constipation Meta-Analysis | It affects an estimated 5–10% of the global population and is more common in women, imposing a significant burden on quality of life and healthcare resources []. | 3 | Šuran Jelena (2026) | IBS and SIBO: Gut Microbiota, Pathophysiology, and Non-Pharmacological Interventions |
| Prebiotics Constipation Meta-Analysis | Designed as a narrative review employing systematic search strategies to ensure comprehensive coverage while accommodating evidence heterogeneity, this study evaluates the efficacy and safety of probiotics, prebiotics, and synbiotics (PP/S) in FC with comorbid depression. | 4 | Dai Q (2026) | Research progress and controversies in the treatment of functional constipation-related depression with probiotics and prebiotics: a narrative review. |
| Prebiotics Constipation Meta-Analysis | Using the terms "probiotic/prebiotic/synbiotic," "functional constipation," and "depression" as subject headings and free-text keywords, we analyzed the available evidence. | 4 | Dai Q (2026) | Research progress and controversies in the treatment of functional constipation-related depression with probiotics and prebiotics: a narrative review. |
| Prebiotics Constipation Meta-Analysis | Current evidence suggests that, in adults (including some older adults), PP/S are associated with improvements in spontaneous bowel movements and stool form (Bristol Stool Form Scale), alongside reductions in abdominal symptoms. | 4 | Dai Q (2026) | Research progress and controversies in the treatment of functional constipation-related depression with probiotics and prebiotics: a narrative review. |
| Prebiotics Constipation Meta-Analysis | Functional constipation (FC) commonly co-occurs with depression, with the microbiota-gut-brain axis providing a biological basis for this association. | 4 | Dai Q (2026) | Research progress and controversies in the treatment of functional constipation-related depression with probiotics and prebiotics: a narrative review. |
Source documents