Peppermint Functional Dyspepsia Meta-Analysis Evidence Table

Structured evidence table for Peppermint Functional Dyspepsia Meta-Analysis, generated from 2 reusable source documents in the Migaku knowledge base.

topicclaimevidence levelcitationsource
Peppermint Functional Dyspepsia Meta-AnalysisThe S1 guideline summarizes the current state of knowledge and allows a targeted approach based on the currently available medical evidence.2Storr M (2026)S1 Guideline of the German Society for Neurogastroenterology and Motility (DGNM) on Functional Dyspepsia (FD), a Disorder of Gut-Brain Interaction (DGBI) [English Language Edition].
Peppermint Functional Dyspepsia Meta-AnalysisFunctional dyspepsia (FD) is common and classified as a disorder of gut-brain interaction (DGBI).2Storr M (2026)S1 Guideline of the German Society for Neurogastroenterology and Motility (DGNM) on Functional Dyspepsia (FD), a Disorder of Gut-Brain Interaction (DGBI) [English Language Edition].
Peppermint Functional Dyspepsia Meta-AnalysisDiagnosis is based on symptoms, which are classified according to the Rome IV criteria, in combination with diagnostic procedures that may include laboratory testing, Helicobacter pylori testing, upper gastrointestinal endoscopy, abdominal ultrasound, and other examinations, depending on the severity, duration, and presence of alarm symptoms.2Storr M (2026)S1 Guideline of the German Society for Neurogastroenterology and Motility (DGNM) on Functional Dyspepsia (FD), a Disorder of Gut-Brain Interaction (DGBI) [English Language Edition].
Peppermint Functional Dyspepsia Meta-AnalysisLow-grade intestinal inflammation with increased mast cells has been observed in some IBS cohorts., A dysbiotic or less diverse gut microbiome may be present in IBS, and small intestinal bacterial overgrowth occurs in a subset of patients; however, routine testing is not of clinical value.3Morrison Savannah (2026)Diagnosis and management of irritable bowel syndrome
Peppermint Functional Dyspepsia Meta-Analysis4 Many studies support a strong psychosocial foundation for IBS, particularly seen in patients who report higher levels of daily stress and those with increased anxiety, depression, and somatic symptoms.There is often a genetic predisposition for IBS.3Morrison Savannah (2026)Diagnosis and management of irritable bowel syndrome
Peppermint Functional Dyspepsia Meta-AnalysisBox 1 Box 2 Avoid routine CT scanning in patients who meet the criteria for IBS () without alarm features (), as this usually adds no diagnostic value, incurs a radiation burden, and can result in false-positive findings that lead to harmful further testing or interventions.3Morrison Savannah (2026)Diagnosis and management of irritable bowel syndrome
Peppermint Functional Dyspepsia Meta-Analysis1 2 Irritable bowel syndrome (IBS) is a common disorder of gut–brain interaction and is characterised by chronic or intermittent abdominal pain or discomfort directly linked to a change of bowel habits.3Morrison Savannah (2026)Diagnosis and management of irritable bowel syndrome
topicPeppermint Functional Dyspepsia Meta-Analysis
claimThe S1 guideline summarizes the current state of knowledge and allows a targeted approach based on the currently available medical evidence.
evidence level2
citationStorr M (2026)
sourceS1 Guideline of the German Society for Neurogastroenterology and Motility (DGNM) on Functional Dyspepsia (FD), a Disorder of Gut-Brain Interaction (DGBI) [English Language Edition].
topicPeppermint Functional Dyspepsia Meta-Analysis
claimFunctional dyspepsia (FD) is common and classified as a disorder of gut-brain interaction (DGBI).
evidence level2
citationStorr M (2026)
sourceS1 Guideline of the German Society for Neurogastroenterology and Motility (DGNM) on Functional Dyspepsia (FD), a Disorder of Gut-Brain Interaction (DGBI) [English Language Edition].
topicPeppermint Functional Dyspepsia Meta-Analysis
claimDiagnosis is based on symptoms, which are classified according to the Rome IV criteria, in combination with diagnostic procedures that may include laboratory testing, Helicobacter pylori testing, upper gastrointestinal endoscopy, abdominal ultrasound, and other examinations, depending on the severity, duration, and presence of alarm symptoms.
evidence level2
citationStorr M (2026)
sourceS1 Guideline of the German Society for Neurogastroenterology and Motility (DGNM) on Functional Dyspepsia (FD), a Disorder of Gut-Brain Interaction (DGBI) [English Language Edition].
topicPeppermint Functional Dyspepsia Meta-Analysis
claimLow-grade intestinal inflammation with increased mast cells has been observed in some IBS cohorts., A dysbiotic or less diverse gut microbiome may be present in IBS, and small intestinal bacterial overgrowth occurs in a subset of patients; however, routine testing is not of clinical value.
evidence level3
citationMorrison Savannah (2026)
sourceDiagnosis and management of irritable bowel syndrome
topicPeppermint Functional Dyspepsia Meta-Analysis
claim4 Many studies support a strong psychosocial foundation for IBS, particularly seen in patients who report higher levels of daily stress and those with increased anxiety, depression, and somatic symptoms.There is often a genetic predisposition for IBS.
evidence level3
citationMorrison Savannah (2026)
sourceDiagnosis and management of irritable bowel syndrome
topicPeppermint Functional Dyspepsia Meta-Analysis
claimBox 1 Box 2 Avoid routine CT scanning in patients who meet the criteria for IBS () without alarm features (), as this usually adds no diagnostic value, incurs a radiation burden, and can result in false-positive findings that lead to harmful further testing or interventions.
evidence level3
citationMorrison Savannah (2026)
sourceDiagnosis and management of irritable bowel syndrome
topicPeppermint Functional Dyspepsia Meta-Analysis
claim1 2 Irritable bowel syndrome (IBS) is a common disorder of gut–brain interaction and is characterised by chronic or intermittent abdominal pain or discomfort directly linked to a change of bowel habits.
evidence level3
citationMorrison Savannah (2026)
sourceDiagnosis and management of irritable bowel syndrome

Source documents

  1. S1 Guideline of the German Society for Neurogastroenterology and Motility (DGNM) on Functional Dyspepsia (FD), a Disorder of Gut-Brain Interaction (DGBI) [English Language Edition].
  2. Diagnosis and management of irritable bowel syndrome