topicPea Protein Muscle Meta-Analysis
claim3 4 Worldwide, obesity is a major public health problem associated with increased morbidity and mortality for all-causes [].
evidence level3
citationColuzzi Flaminia (2026)
sourceNew Adjuvant Therapies for Obesity-Related Disorders Associated with Meta-Neuroinflammation
topicPea Protein Muscle Meta-Analysis
claimAlthough obesity is recognized as a high-risk condition for the development of other chronic degenerative non-communicable diseases, this pathology has been declared as a disease per se that leads to a reduction in the quality and expectancy of life [].
evidence level3
citationColuzzi Flaminia (2026)
sourceNew Adjuvant Therapies for Obesity-Related Disorders Associated with Meta-Neuroinflammation
topicPea Protein Muscle Meta-Analysis
claim5 3 6 7 8 In obesity patients, the adipocyte hypertrophy, visceral and ectopic adiposity, increased production of adipokines with anorexigenic function, such as leptin, and of a plethora of pro-inflammatory cytokines, such as tumor necrosis factor-α (TNF-α), interleukin (IL)-6, IL-1β, and resistin, which predisposes the organism to the adiposopathy (or “sick fat”) [].
evidence level3
citationColuzzi Flaminia (2026)
sourceNew Adjuvant Therapies for Obesity-Related Disorders Associated with Meta-Neuroinflammation
topicPea Protein Muscle Meta-Analysis
claim1 2 Obesity is a complex, heterogeneous, chronic, and progressive disease, which substantially affects more than 890 million (13%) adults [].
evidence level3
citationColuzzi Flaminia (2026)
sourceNew Adjuvant Therapies for Obesity-Related Disorders Associated with Meta-Neuroinflammation
topicPea Protein Muscle Meta-Analysis
claimAccording to the internationally used definition, MetS is characterized by having at least three out of several possible risk factors, including high blood pressure, hypertriglyceridemia, low levels of HDL cholesterol, elevated fasting glucose, and central obesity ().
evidence level3
citationWang Song-nan (2026)
sourceBranched-chain amino acids from plants and the metabolic syndrome: pathways and pharmacological applications
topicPea Protein Muscle Meta-Analysis
claimα p p 6 7 9 9 10 6 High levels of TNF-, IL-6, and CRP are associated with insulin resistance, endothelial dysfunction, and atherogenesis (,,).
evidence level3
citationWang Song-nan (2026)
sourceBranched-chain amino acids from plants and the metabolic syndrome: pathways and pharmacological applications
topicPea Protein Muscle Meta-Analysis
claimSuch increases appear to be closely linked to MetS, type 2T2DM, and CVD risk (,).
evidence level3
citationWang Song-nan (2026)
sourceBranched-chain amino acids from plants and the metabolic syndrome: pathways and pharmacological applications
topicPea Protein Muscle Meta-Analysis
claim1 1 The metabolic syndrome (MetS), one of the most significant public health problems of the 21st century, is characterized by central obesity, insulin resistance, hypertension, and dyslipidemia.
evidence level3
citationWang Song-nan (2026)
sourceBranched-chain amino acids from plants and the metabolic syndrome: pathways and pharmacological applications