Structured evidence table for Oral Ceramides Skin Hydration Meta-Analysis, generated from 2 reusable source documents in the Migaku knowledge base.
| topic | claim | evidence level | citation | source |
|---|---|---|---|---|
| Oral Ceramides Skin Hydration Meta-Analysis | Background Our search for plant-derived ceramides from sustainable sources led to the discovery of ceramides and glucosylceramides in wine lees. | 2 | Sanjaya A (2024) | Efficacy and Safety of Oral Administration of Wine Lees Extract (WLE)-Derived Ceramides and Glucosylceramides in Enhancing Skin Barrier Function: A Randomized, Double-Blind, Placebo-Controlled Study. |
| Oral Ceramides Skin Hydration Meta-Analysis | Objective This study evaluated the efficacy and safety of wine lees extract (WLE)-derived ceramides and glucosylceramides in enhancing skin barrier function. | 2 | Sanjaya A (2024) | Efficacy and Safety of Oral Administration of Wine Lees Extract (WLE)-Derived Ceramides and Glucosylceramides in Enhancing Skin Barrier Function: A Randomized, Double-Blind, Placebo-Controlled Study. |
| Oral Ceramides Skin Hydration Meta-Analysis | Quercetin, a flavonoid found in fruits such as apples and onions, has demonstrated significant potential in reducing the production of pro‐inflammatory cytokines (TNF‐α, IL‐6), inhibiting the release of inflammatory mediators, and alleviating atopic dermatitis (AD) and skin irritation [,]. | 4 | Yang Miaohong (2025) | Oral Prescription Containing Ceramide, Proanthocyanidins, Quercetin, and Citrus Flavonoids Improves Sensitive Skin in Mice by Modulating Inflammation, Skin Barrier Function, and Gut Microbiota |
| Oral Ceramides Skin Hydration Meta-Analysis | Citrus flavonoids, such as those found in oranges and lemons, have been shown to promote skin hydration and restore barrier function by enhancing collagen synthesis and promoting keratinocyte differentiation [,]. | 4 | Yang Miaohong (2025) | Oral Prescription Containing Ceramide, Proanthocyanidins, Quercetin, and Citrus Flavonoids Improves Sensitive Skin in Mice by Modulating Inflammation, Skin Barrier Function, and Gut Microbiota |
| Oral Ceramides Skin Hydration Meta-Analysis | By improving skin hydration and reducing water loss, these formulations offer promising avenues for alleviating the discomfort associated with sensitive skin and improving overall skin health []. | 4 | Yang Miaohong (2025) | Oral Prescription Containing Ceramide, Proanthocyanidins, Quercetin, and Citrus Flavonoids Improves Sensitive Skin in Mice by Modulating Inflammation, Skin Barrier Function, and Gut Microbiota |
| Oral Ceramides Skin Hydration Meta-Analysis | AEW AQP3 DNFB ELISA ET‐1 FLG HE IFN‐γ IL‐13 IL‐4 IL‐6 LOR TEWL TRPV1 VEGFA 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 The pathogenesis of sensitive skin involves the interaction of various cytokines and receptor pathways [,]. | 4 | Yang Miaohong (2025) | Oral Prescription Containing Ceramide, Proanthocyanidins, Quercetin, and Citrus Flavonoids Improves Sensitive Skin in Mice by Modulating Inflammation, Skin Barrier Function, and Gut Microbiota |
Source documents