Omega-7 Skin Hydration Randomized Trial Evidence Table

Structured evidence table for Omega-7 Skin Hydration Randomized Trial, generated from 2 reusable source documents in the Migaku knowledge base.

topicclaimevidence levelcitationsource
Omega-7 Skin Hydration Randomized TrialAdditionally, palmitoleic acid supplementation significantly improved skin hydration and elasticity in middle-aged women [].2Koh Young Gue (2023)Efficacy and safety of oral palmitoleic acid supplementation for skin barrier improvement: A 12-week, randomized, double-blinded, placebo-controlled study
Omega-7 Skin Hydration Randomized Trial2 Compared with baseline, skin hydration significantly increased at Week 6 in both groups, without significant differences between intervention and control groups.2Koh Young Gue (2023)Efficacy and safety of oral palmitoleic acid supplementation for skin barrier improvement: A 12-week, randomized, double-blinded, placebo-controlled study
Omega-7 Skin Hydration Randomized TrialHowever, after 12 weeks, skin hydration of the intervention group significantly increased as compared with the skin hydration of the control group on the left, right periorbital area, and average values ().2Koh Young Gue (2023)Efficacy and safety of oral palmitoleic acid supplementation for skin barrier improvement: A 12-week, randomized, double-blinded, placebo-controlled study
Omega-7 Skin Hydration Randomized TrialPalmitoleic acid (C16:1) is a common omega-7 (ω-7) monounsaturated fatty acid constituting approximately 7% of the visceral fatty acids produced by Alaskan pollock [] and has beneficial effects on human metabolism through promotion of cardiac growth, proliferation of pancreatic β-cells, regulation of lipogenesis and fatty acid desaturation in adipocytes, and alleviation of inflammation [].2Koh Young Gue (2023)Efficacy and safety of oral palmitoleic acid supplementation for skin barrier improvement: A 12-week, randomized, double-blinded, placebo-controlled study
Omega-7 Skin Hydration Randomized TrialFSG treatment resulted in faster re-epithelialization and reduced wound size at day 14 compared to FBD (50.2% vs.4Stone R (2021)Accelerated Wound Closure of Deep Partial Thickness Burns with Acellular Fish Skin Graft.
Omega-7 Skin Hydration Randomized TrialHere we show that FSG integrated faster without increased contraction, resulting in quicker wound closure without skin graft application which suggests FSG improved burn wound healing over FBD.4Stone R (2021)Accelerated Wound Closure of Deep Partial Thickness Burns with Acellular Fish Skin Graft.
Omega-7 Skin Hydration Randomized TrialThermal injuries are caused by exposure to a variety of sources, and split thickness skin grafts are the gold standard treatment for severe burns; however, they may be impossible when there is no donor skin available.4Stone R (2021)Accelerated Wound Closure of Deep Partial Thickness Burns with Acellular Fish Skin Graft.
Omega-7 Skin Hydration Randomized TrialLarge total body surface area burns leave patients with limited donor site availability and create a need for treatments capable of achieving early and complete coverage that can also retain normal skin function.4Stone R (2021)Accelerated Wound Closure of Deep Partial Thickness Burns with Acellular Fish Skin Graft.
topicOmega-7 Skin Hydration Randomized Trial
claimAdditionally, palmitoleic acid supplementation significantly improved skin hydration and elasticity in middle-aged women [].
evidence level2
citationKoh Young Gue (2023)
sourceEfficacy and safety of oral palmitoleic acid supplementation for skin barrier improvement: A 12-week, randomized, double-blinded, placebo-controlled study
topicOmega-7 Skin Hydration Randomized Trial
claim2 Compared with baseline, skin hydration significantly increased at Week 6 in both groups, without significant differences between intervention and control groups.
evidence level2
citationKoh Young Gue (2023)
sourceEfficacy and safety of oral palmitoleic acid supplementation for skin barrier improvement: A 12-week, randomized, double-blinded, placebo-controlled study
topicOmega-7 Skin Hydration Randomized Trial
claimHowever, after 12 weeks, skin hydration of the intervention group significantly increased as compared with the skin hydration of the control group on the left, right periorbital area, and average values ().
evidence level2
citationKoh Young Gue (2023)
sourceEfficacy and safety of oral palmitoleic acid supplementation for skin barrier improvement: A 12-week, randomized, double-blinded, placebo-controlled study
topicOmega-7 Skin Hydration Randomized Trial
claimPalmitoleic acid (C16:1) is a common omega-7 (ω-7) monounsaturated fatty acid constituting approximately 7% of the visceral fatty acids produced by Alaskan pollock [] and has beneficial effects on human metabolism through promotion of cardiac growth, proliferation of pancreatic β-cells, regulation of lipogenesis and fatty acid desaturation in adipocytes, and alleviation of inflammation [].
evidence level2
citationKoh Young Gue (2023)
sourceEfficacy and safety of oral palmitoleic acid supplementation for skin barrier improvement: A 12-week, randomized, double-blinded, placebo-controlled study
topicOmega-7 Skin Hydration Randomized Trial
claimFSG treatment resulted in faster re-epithelialization and reduced wound size at day 14 compared to FBD (50.2% vs.
evidence level4
citationStone R (2021)
sourceAccelerated Wound Closure of Deep Partial Thickness Burns with Acellular Fish Skin Graft.
topicOmega-7 Skin Hydration Randomized Trial
claimHere we show that FSG integrated faster without increased contraction, resulting in quicker wound closure without skin graft application which suggests FSG improved burn wound healing over FBD.
evidence level4
citationStone R (2021)
sourceAccelerated Wound Closure of Deep Partial Thickness Burns with Acellular Fish Skin Graft.
topicOmega-7 Skin Hydration Randomized Trial
claimThermal injuries are caused by exposure to a variety of sources, and split thickness skin grafts are the gold standard treatment for severe burns; however, they may be impossible when there is no donor skin available.
evidence level4
citationStone R (2021)
sourceAccelerated Wound Closure of Deep Partial Thickness Burns with Acellular Fish Skin Graft.
topicOmega-7 Skin Hydration Randomized Trial
claimLarge total body surface area burns leave patients with limited donor site availability and create a need for treatments capable of achieving early and complete coverage that can also retain normal skin function.
evidence level4
citationStone R (2021)
sourceAccelerated Wound Closure of Deep Partial Thickness Burns with Acellular Fish Skin Graft.

Source documents

  1. Efficacy and safety of oral palmitoleic acid supplementation for skin barrier improvement: A 12-week, randomized, double-blinded, placebo-controlled study
  2. Accelerated Wound Closure of Deep Partial Thickness Burns with Acellular Fish Skin Graft.