Omega-3 Memory Meta-Analysis Evidence Table

Structured evidence table for Omega-3 Memory Meta-Analysis, generated from 3 reusable source documents in the Migaku knowledge base.

topicclaimevidence levelcitationsource
Omega-3 Memory Meta-AnalysisConcurrently, the number of individuals affected by dementia is anticipated to nearly triple by 2050, with associated treatment costs projected to reach US$2.8 trillion by 2030 [].1Liu Xing (2026)Nutritional supplements and cognition in healthy aging and mild cognitive impairment patients: a systematic review and network meta-analysis
Omega-3 Memory Meta-AnalysisIn addition, omega-3 fatty acids support synaptic plasticity and exert anti-inflammatory effects; however, evidence is mixed, as randomized trials in healthy older adults show limited benefits [,], while several analyses report modest improvements in aged or MCI patients [,].1Liu Xing (2026)Nutritional supplements and cognition in healthy aging and mild cognitive impairment patients: a systematic review and network meta-analysis
Omega-3 Memory Meta-AnalysisObservational studies and recent trials involving antioxidant nutrients, such as pomegranate juice and resveratrol, alongside polyphenols, suggest potential protection for specific cognitive domains (e.g., memory) and reduced dementia risk, although effects are heterogeneous and causality remains unconfirmed [,].1Liu Xing (2026)Nutritional supplements and cognition in healthy aging and mild cognitive impairment patients: a systematic review and network meta-analysis
Omega-3 Memory Meta-Analysis1 2 3 4 5 6 7 8 9 10 The World Health Organization (WHO) projects that by 2050, the global population aged 60 and above will reach 2.1 billion, highlighting the inevitability of global aging [].1Liu Xing (2026)Nutritional supplements and cognition in healthy aging and mild cognitive impairment patients: a systematic review and network meta-analysis
Omega-3 Memory Meta-AnalysisConsequently, identifying modifiable risk factors to prevent or delay cognitive decline is of critical public health importance [,].4Liao Zheng-Bin (2026)The association between omega-3 supplementation and cognitive decline in older adults
Omega-3 Memory Meta-AnalysisBy elucidating these specific neurobiological pathways, we aim to provide clinical evidence that informs the debate regarding the role of omega-3 fatty acids supplementation in slowing cognitive decline.4Liao Zheng-Bin (2026)The association between omega-3 supplementation and cognitive decline in older adults
Omega-3 Memory Meta-Analysis29 30 31 This study employed three commonly used cognitive scales to assess longitudinal trajectories associated with omega-3 supplementation: the Mini-Mental State Examination (MMSE), the Alzheimer’s Disease Assessment Scale–Cognitive Subscale 13 (ADAS-Cog13), and the Clinical Dementia Rating–Sum of Boxes (CDR-SB).4Liao Zheng-Bin (2026)The association between omega-3 supplementation and cognitive decline in older adults
Omega-3 Memory Meta-Analysis1 2 3 4 5 6 7 8 9 10 11 12 13 14 in vivo Alzheimer’s disease (AD), the leading cause of dementia, imposes a growing global public health burden [].4Liao Zheng-Bin (2026)The association between omega-3 supplementation and cognitive decline in older adults
Omega-3 Memory Meta-AnalysisValidation of the Mizan Meta-Memory and Meta-Concentration Scale for Students (MMSS) among Nigerian health care students.4Adesola AA (2026)Validation of the Mizan Meta-Memory and Meta-Concentration Scale for Students (MMSS) among Nigerian health care students.
topicOmega-3 Memory Meta-Analysis
claimConcurrently, the number of individuals affected by dementia is anticipated to nearly triple by 2050, with associated treatment costs projected to reach US$2.8 trillion by 2030 [].
evidence level1
citationLiu Xing (2026)
sourceNutritional supplements and cognition in healthy aging and mild cognitive impairment patients: a systematic review and network meta-analysis
topicOmega-3 Memory Meta-Analysis
claimIn addition, omega-3 fatty acids support synaptic plasticity and exert anti-inflammatory effects; however, evidence is mixed, as randomized trials in healthy older adults show limited benefits [,], while several analyses report modest improvements in aged or MCI patients [,].
evidence level1
citationLiu Xing (2026)
sourceNutritional supplements and cognition in healthy aging and mild cognitive impairment patients: a systematic review and network meta-analysis
topicOmega-3 Memory Meta-Analysis
claimObservational studies and recent trials involving antioxidant nutrients, such as pomegranate juice and resveratrol, alongside polyphenols, suggest potential protection for specific cognitive domains (e.g., memory) and reduced dementia risk, although effects are heterogeneous and causality remains unconfirmed [,].
evidence level1
citationLiu Xing (2026)
sourceNutritional supplements and cognition in healthy aging and mild cognitive impairment patients: a systematic review and network meta-analysis
topicOmega-3 Memory Meta-Analysis
claim1 2 3 4 5 6 7 8 9 10 The World Health Organization (WHO) projects that by 2050, the global population aged 60 and above will reach 2.1 billion, highlighting the inevitability of global aging [].
evidence level1
citationLiu Xing (2026)
sourceNutritional supplements and cognition in healthy aging and mild cognitive impairment patients: a systematic review and network meta-analysis
topicOmega-3 Memory Meta-Analysis
claimConsequently, identifying modifiable risk factors to prevent or delay cognitive decline is of critical public health importance [,].
evidence level4
citationLiao Zheng-Bin (2026)
sourceThe association between omega-3 supplementation and cognitive decline in older adults
topicOmega-3 Memory Meta-Analysis
claimBy elucidating these specific neurobiological pathways, we aim to provide clinical evidence that informs the debate regarding the role of omega-3 fatty acids supplementation in slowing cognitive decline.
evidence level4
citationLiao Zheng-Bin (2026)
sourceThe association between omega-3 supplementation and cognitive decline in older adults
topicOmega-3 Memory Meta-Analysis
claim29 30 31 This study employed three commonly used cognitive scales to assess longitudinal trajectories associated with omega-3 supplementation: the Mini-Mental State Examination (MMSE), the Alzheimer’s Disease Assessment Scale–Cognitive Subscale 13 (ADAS-Cog13), and the Clinical Dementia Rating–Sum of Boxes (CDR-SB).
evidence level4
citationLiao Zheng-Bin (2026)
sourceThe association between omega-3 supplementation and cognitive decline in older adults
topicOmega-3 Memory Meta-Analysis
claim1 2 3 4 5 6 7 8 9 10 11 12 13 14 in vivo Alzheimer’s disease (AD), the leading cause of dementia, imposes a growing global public health burden [].
evidence level4
citationLiao Zheng-Bin (2026)
sourceThe association between omega-3 supplementation and cognitive decline in older adults
topicOmega-3 Memory Meta-Analysis
claimValidation of the Mizan Meta-Memory and Meta-Concentration Scale for Students (MMSS) among Nigerian health care students.
evidence level4
citationAdesola AA (2026)
sourceValidation of the Mizan Meta-Memory and Meta-Concentration Scale for Students (MMSS) among Nigerian health care students.

Source documents

  1. Nutritional supplements and cognition in healthy aging and mild cognitive impairment patients: a systematic review and network meta-analysis
  2. The association between omega-3 supplementation and cognitive decline in older adults
  3. Validation of the Mizan Meta-Memory and Meta-Concentration Scale for Students (MMSS) among Nigerian health care students.