topicOmega-3 Cognitive Function Meta-Analysis
claimThis review summarizes current evidence on nutritional compounds that target aging-related pathways, focusing on interventions that influence mitochondrial health, cognitive performance, immune function, metabolic regulation, and maintenance of muscle mass in older adults.
evidence level4
citationKurtz JA (2026)
sourceTargeted Supplementation and Nutritional Strategies for Healthy Aging: A Review of Physiological and Molecular Benefits.
topicOmega-3 Cognitive Function Meta-Analysis
claimRecent findings Evidence indicates that several targeted nutrients, including protein, probiotics, antioxidants, and emerging mitochondrial-support compounds, may contribute to healthy aging.
evidence level4
citationKurtz JA (2026)
sourceTargeted Supplementation and Nutritional Strategies for Healthy Aging: A Review of Physiological and Molecular Benefits.
topicOmega-3 Cognitive Function Meta-Analysis
claimA personalized, evidence-informed supplementation strategy integrated with exercise and balanced nutrition may help optimize physiological function in aging adults.
evidence level4
citationKurtz JA (2026)
sourceTargeted Supplementation and Nutritional Strategies for Healthy Aging: A Review of Physiological and Molecular Benefits.
topicOmega-3 Cognitive Function Meta-Analysis
claimPurpose of review Aging is marked by progressive physiological decline driven by chronic inflammation, mitochondrial dysfunction, and impaired metabolic and musculoskeletal resilience.
evidence level4
citationKurtz JA (2026)
sourceTargeted Supplementation and Nutritional Strategies for Healthy Aging: A Review of Physiological and Molecular Benefits.
topicOmega-3 Cognitive Function Meta-Analysis
claimConsequently, identifying modifiable risk factors to prevent or delay cognitive decline is of critical public health importance [,].
evidence level4
citationLiao Zheng-Bin (2026)
sourceThe association between omega-3 supplementation and cognitive decline in older adults
topicOmega-3 Cognitive Function Meta-Analysis
claimBy elucidating these specific neurobiological pathways, we aim to provide clinical evidence that informs the debate regarding the role of omega-3 fatty acids supplementation in slowing cognitive decline.
evidence level4
citationLiao Zheng-Bin (2026)
sourceThe association between omega-3 supplementation and cognitive decline in older adults
topicOmega-3 Cognitive Function Meta-Analysis
claim29 30 31 This study employed three commonly used cognitive scales to assess longitudinal trajectories associated with omega-3 supplementation: the Mini-Mental State Examination (MMSE), the Alzheimer’s Disease Assessment Scale–Cognitive Subscale 13 (ADAS-Cog13), and the Clinical Dementia Rating–Sum of Boxes (CDR-SB).
evidence level4
citationLiao Zheng-Bin (2026)
sourceThe association between omega-3 supplementation and cognitive decline in older adults
topicOmega-3 Cognitive Function Meta-Analysis
claim1 2 3 4 5 6 7 8 9 10 11 12 13 14 in vivo Alzheimer’s disease (AD), the leading cause of dementia, imposes a growing global public health burden [].
evidence level4
citationLiao Zheng-Bin (2026)
sourceThe association between omega-3 supplementation and cognitive decline in older adults