Structured evidence table for Olive Leaf Metabolic Health Randomized Trial, generated from 2 reusable source documents in the Migaku knowledge base.
| topic | claim | evidence level | citation | source |
|---|---|---|---|---|
| Olive Leaf Metabolic Health Randomized Trial | Introduction Menopause marks the end of a woman's reproductive cycle and is associated with a decline in estrogen levels. | 2 | Lasfar A (2025) | Effects of olive leaf extract supplementation on systemic markers of tissue aging and remodeling in postmenopausal women: a randomized controlled trial with exploratory skin outcomes. |
| Olive Leaf Metabolic Health Randomized Trial | This hormonal shift accelerates systemic aging processes, affecting metabolic regulation, cardiovascular risk, and connective tissue integrity. | 2 | Lasfar A (2025) | Effects of olive leaf extract supplementation on systemic markers of tissue aging and remodeling in postmenopausal women: a randomized controlled trial with exploratory skin outcomes. |
| Olive Leaf Metabolic Health Randomized Trial | Results Elastin levels significantly increased in the placebo group while they remained stable in the OLE group [-6.3 [-12.0; -0.05], p = 0.033], but not after correction for multiple testing ( p adj = 0.0825). | 2 | Lasfar A (2025) | Effects of olive leaf extract supplementation on systemic markers of tissue aging and remodeling in postmenopausal women: a randomized controlled trial with exploratory skin outcomes. |
| Olive Leaf Metabolic Health Randomized Trial | Major risk factors include hypercholesterolemia, hypertension, diabetes, infections, and smoking [,]. | 3 | Morvaridzadeh Mojgan (2025) | Polyphenol-Microbiota Interactions in Atherosclerosis: The Role of Hydroxytyrosol and Tyrosol in Modulating Inflammation and Oxidative Stress |
| Olive Leaf Metabolic Health Randomized Trial | Emerging evidence highlights a bidirectional relationship between the gut microbiota and dietary polyphenols, particularly in the modulation of inflammation and lipid metabolism; two central processes in atherosclerosis [,]. | 3 | Morvaridzadeh Mojgan (2025) | Polyphenol-Microbiota Interactions in Atherosclerosis: The Role of Hydroxytyrosol and Tyrosol in Modulating Inflammation and Oxidative Stress |
| Olive Leaf Metabolic Health Randomized Trial | Dysbiosis has been increasingly associated with CVD development and atherosclerosis progression [,,]. | 3 | Morvaridzadeh Mojgan (2025) | Polyphenol-Microbiota Interactions in Atherosclerosis: The Role of Hydroxytyrosol and Tyrosol in Modulating Inflammation and Oxidative Stress |
| Olive Leaf Metabolic Health Randomized Trial | 1 2 3 4 5 6 Cardiovascular disease (CVD) remains the leading cause of mortality worldwide, accounting for approximately 32% of annual deaths, with atherosclerotic cardiovascular disease (ASCVD) as the primary contributor [,]. | 3 | Morvaridzadeh Mojgan (2025) | Polyphenol-Microbiota Interactions in Atherosclerosis: The Role of Hydroxytyrosol and Tyrosol in Modulating Inflammation and Oxidative Stress |
Source documents