evidence table

Olive Leaf Extract Sleep Randomized Trial Evidence Table

Structured evidence table for Olive Leaf Extract Sleep Randomized Trial, generated from 2 reusable source documents in the Migaku knowledge base.

topicclaimevidence levelcitationsource
Olive Leaf Extract Sleep Randomized TrialResults At day 60, both VL-G-A57 and VL-G-E12 significantly reduced Perceived Stress Scale (PSS) scores compared to placebo (p Conclusion The study concluded that both VL-G-A57 and VL-G-E12 were associated with reductions in stress, fatigue, and anxiety while improving mood and sleep quality.2McKinney E (2026)Effects of multi-herb and ashwagandha root formulas on stress modulation: a randomized, double-blind, placebo-controlled clinical study.
Olive Leaf Extract Sleep Randomized TrialBackground Chronic stress is detrimental to the maintenance of the main response system - the hypothalamic-pituitary-adrenal (HPA) axis.2McKinney E (2026)Effects of multi-herb and ashwagandha root formulas on stress modulation: a randomized, double-blind, placebo-controlled clinical study.
Olive Leaf Extract Sleep Randomized TrialThe current study aimed to investigate the efficacy of two plant-based adaptogens, a formula containing Rhodiola, holy basil and Schisandra chinensis (VL-G-A57) and a full-spectrum ashwagandha (VL-G-E12), on stress and related symptoms in individuals with high stress.2McKinney E (2026)Effects of multi-herb and ashwagandha root formulas on stress modulation: a randomized, double-blind, placebo-controlled clinical study.
Olive Leaf Extract Sleep Randomized TrialFollowing a nutritious, well-balanced diet has been found to lower the risk of depression [], whereas consuming diets high in processed and sugary foods and low in fiber and healthy fats correlates with a higher risk of depression [,,,].3Martínez-Zamora Lorena (2025)Novel Ingredients: Hydroxytyrosol as a Neuroprotective Agent; What Is New on the Horizon?
Olive Leaf Extract Sleep Randomized Trial13 14 15 One of the most important phytochemicals found in olive by-products is hydroxytyrosol (HXT), which has garnered attention during the last twenty years due to its important health benefits.3Martínez-Zamora Lorena (2025)Novel Ingredients: Hydroxytyrosol as a Neuroprotective Agent; What Is New on the Horizon?
Olive Leaf Extract Sleep Randomized TrialHXT is associated with neuroprotective effects, which have prompted research into its potential to prevent cognitive decline, particularly in relation to Alzheimer’s disease [].3Martínez-Zamora Lorena (2025)Novel Ingredients: Hydroxytyrosol as a Neuroprotective Agent; What Is New on the Horizon?
Olive Leaf Extract Sleep Randomized Trial1 2 3 4 5 6 7 8 9 Food is an essential part of our lives, transcending its basic role of providing nutrients necessary for human survival.3Martínez-Zamora Lorena (2025)Novel Ingredients: Hydroxytyrosol as a Neuroprotective Agent; What Is New on the Horizon?
topicOlive Leaf Extract Sleep Randomized Trial
claimResults At day 60, both VL-G-A57 and VL-G-E12 significantly reduced Perceived Stress Scale (PSS) scores compared to placebo (p Conclusion The study concluded that both VL-G-A57 and VL-G-E12 were associated with reductions in stress, fatigue, and anxiety while improving mood and sleep quality.
evidence level2
citationMcKinney E (2026)
sourceEffects of multi-herb and ashwagandha root formulas on stress modulation: a randomized, double-blind, placebo-controlled clinical study.
topicOlive Leaf Extract Sleep Randomized Trial
claimBackground Chronic stress is detrimental to the maintenance of the main response system - the hypothalamic-pituitary-adrenal (HPA) axis.
evidence level2
citationMcKinney E (2026)
sourceEffects of multi-herb and ashwagandha root formulas on stress modulation: a randomized, double-blind, placebo-controlled clinical study.
topicOlive Leaf Extract Sleep Randomized Trial
claimThe current study aimed to investigate the efficacy of two plant-based adaptogens, a formula containing Rhodiola, holy basil and Schisandra chinensis (VL-G-A57) and a full-spectrum ashwagandha (VL-G-E12), on stress and related symptoms in individuals with high stress.
evidence level2
citationMcKinney E (2026)
sourceEffects of multi-herb and ashwagandha root formulas on stress modulation: a randomized, double-blind, placebo-controlled clinical study.
topicOlive Leaf Extract Sleep Randomized Trial
claimFollowing a nutritious, well-balanced diet has been found to lower the risk of depression [], whereas consuming diets high in processed and sugary foods and low in fiber and healthy fats correlates with a higher risk of depression [,,,].
evidence level3
citationMartínez-Zamora Lorena (2025)
sourceNovel Ingredients: Hydroxytyrosol as a Neuroprotective Agent; What Is New on the Horizon?
topicOlive Leaf Extract Sleep Randomized Trial
claim13 14 15 One of the most important phytochemicals found in olive by-products is hydroxytyrosol (HXT), which has garnered attention during the last twenty years due to its important health benefits.
evidence level3
citationMartínez-Zamora Lorena (2025)
sourceNovel Ingredients: Hydroxytyrosol as a Neuroprotective Agent; What Is New on the Horizon?
topicOlive Leaf Extract Sleep Randomized Trial
claimHXT is associated with neuroprotective effects, which have prompted research into its potential to prevent cognitive decline, particularly in relation to Alzheimer’s disease [].
evidence level3
citationMartínez-Zamora Lorena (2025)
sourceNovel Ingredients: Hydroxytyrosol as a Neuroprotective Agent; What Is New on the Horizon?
topicOlive Leaf Extract Sleep Randomized Trial
claim1 2 3 4 5 6 7 8 9 Food is an essential part of our lives, transcending its basic role of providing nutrients necessary for human survival.
evidence level3
citationMartínez-Zamora Lorena (2025)
sourceNovel Ingredients: Hydroxytyrosol as a Neuroprotective Agent; What Is New on the Horizon?

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Source documents

  1. Effects of multi-herb and ashwagandha root formulas on stress modulation: a randomized, double-blind, placebo-controlled clinical study.
  2. Novel Ingredients: Hydroxytyrosol as a Neuroprotective Agent; What Is New on the Horizon?