topicNiacinamide Skin Health Randomized Trial
claimNeutral donor pH (7.4) increased NIA permeation by roughly twofold compared with acidic pH (5.0) in both membrane types.
evidence level4
citationSjöberg T (2026)
sourceEffect of pH on niacinamide skin permeation.
topicNiacinamide Skin Health Randomized Trial
claimCorrespondingly, pH 7.4 decreased R mem and increased C eff , indicating pH driven changes in SC lipid organization and dielectric behavior.
evidence level4
citationSjöberg T (2026)
sourceEffect of pH on niacinamide skin permeation.
topicNiacinamide Skin Health Randomized Trial
claimIn conclusion, donor phase pH is a critical determinant of NIA skin permeation, primarily through reversible modulation of SC lipid structure and transport pathways.
evidence level4
citationSjöberg T (2026)
sourceEffect of pH on niacinamide skin permeation.
topicNiacinamide Skin Health Randomized Trial
claimNiacinamide (NIA) is a widely used skincare ingredient with established benefits for skin barrier support, inflammation reduction, and dermal health.
evidence level4
citationSjöberg T (2026)
sourceEffect of pH on niacinamide skin permeation.
topicNiacinamide Skin Health Randomized Trial
claimRheological measurements showed that the storage modulus ( G ') increased from 1795 Pa (Gel) to 4699 Pa (NTp-Gel), indicating improved mechanical strength.
evidence level4
citationXiong Z (2025)
sourcePreparation and Evaluation of Tangerine Peel-Niacinamide-Gelatin Soft Candy with Antiaging Potential.
topicNiacinamide Skin Health Randomized Trial
claimWith the growing recognition of functional foods in regulating physiological functions and delaying chronic disease progression, the development of innovative dosage forms has become a major research focus.
evidence level4
citationXiong Z (2025)
sourcePreparation and Evaluation of Tangerine Peel-Niacinamide-Gelatin Soft Candy with Antiaging Potential.
topicNiacinamide Skin Health Randomized Trial
claimThis study developed a tangerine peel-niacinamide-gelatin (NTp-Gel) soft candy with enhanced antioxidant activity, physicochemical stability, and biological safety.
evidence level4
citationXiong Z (2025)
sourcePreparation and Evaluation of Tangerine Peel-Niacinamide-Gelatin Soft Candy with Antiaging Potential.