Structured evidence table for N-Acetylcysteine Anxiety Meta-Analysis, generated from 2 reusable source documents in the Migaku knowledge base.
| topic | claim | evidence level | citation | source |
|---|---|---|---|---|
| N-Acetylcysteine Anxiety Meta-Analysis | Additionally, we performed a risk-of-bias analysis of the studies compatible with the RoB2 tool. | 1 | Tortajada J (2026) | Clinical outcomes of mitochondrial-enhancing nutraceutical supplementation in psychiatric disorders: A systematic review. |
| N-Acetylcysteine Anxiety Meta-Analysis | Overall, the risk of bias was high, and the methodological quality was generally low. | 1 | Tortajada J (2026) | Clinical outcomes of mitochondrial-enhancing nutraceutical supplementation in psychiatric disorders: A systematic review. |
| N-Acetylcysteine Anxiety Meta-Analysis | Background Nutraceutical supplementation targeting mitochondrial function has been proposed as a beneficial therapeutic strategy to improve physical and mental health in psychiatric patients. | 1 | Tortajada J (2026) | Clinical outcomes of mitochondrial-enhancing nutraceutical supplementation in psychiatric disorders: A systematic review. |
| N-Acetylcysteine Anxiety Meta-Analysis | Aims To summarise the results of studies evaluating nutraceutical supplementation targeting mitochondrial function in patients with psychiatric disorders. | 1 | Tortajada J (2026) | Clinical outcomes of mitochondrial-enhancing nutraceutical supplementation in psychiatric disorders: A systematic review. |
| N-Acetylcysteine Anxiety Meta-Analysis | Individuals with PTSD exhibit sustained hyperactivation of the amygdala and disturbances of the prefrontal-limbic inhibitory network, associated with elevated neuroinflammatory signaling []. | 1 | Ahmed Mohamed Awad E. (2026) | N-acetylcysteine for patients with alcohol use disorder, post-traumatic stress disorder, and their co-occurrence: a systematic review of placebo-controlled randomized trials |
| N-Acetylcysteine Anxiety Meta-Analysis | Beyond traditional models, recent evidence highlights that severe stress exposure, such as war-related trauma, can trigger profound depressive reactions and post-traumatic symptoms through a cascade of inflammatory activation, mitochondrial dysfunction, and redox imbalance []. | 1 | Ahmed Mohamed Awad E. (2026) | N-acetylcysteine for patients with alcohol use disorder, post-traumatic stress disorder, and their co-occurrence: a systematic review of placebo-controlled randomized trials |
| N-Acetylcysteine Anxiety Meta-Analysis | Although limited evidence directly targeted the effect of NAC on co-occurring PTSD and AUD, (Back et al., 2025) found that NAC showed good tolerability and reductions in craving symptoms, but results did not reach statistically significant group differences [,]. | 1 | Ahmed Mohamed Awad E. (2026) | N-acetylcysteine for patients with alcohol use disorder, post-traumatic stress disorder, and their co-occurrence: a systematic review of placebo-controlled randomized trials |
| N-Acetylcysteine Anxiety Meta-Analysis | 1 2 3 4 5 Post-traumatic stress disorder (PTSD) and alcohol use disorder (AUD) are considered major contributors to the burden of psychiatric disease worldwide []. | 1 | Ahmed Mohamed Awad E. (2026) | N-acetylcysteine for patients with alcohol use disorder, post-traumatic stress disorder, and their co-occurrence: a systematic review of placebo-controlled randomized trials |
Source documents