Myo-Inositol Sleep Quality Randomized Trial Evidence Table

Structured evidence table for Myo-Inositol Sleep Quality Randomized Trial, generated from 2 reusable source documents in the Migaku knowledge base.

topicclaimevidence levelcitationsource
Myo-Inositol Sleep Quality Randomized TrialThe global prevalence of PCOS increased from 36.7 to 69.5 million between 1990 and 2021.3Subakathulla Sumayyah (2026)Redox-endocrine triad in PCOS: can vitamin D, myo-inositol, and melatonin synergize as bioactive cocktails?
Myo-Inositol Sleep Quality Randomized TrialEmerging evidence underscores that OS is not a mere byproduct of metabolic imbalance but a central driver that disrupts insulin signaling, amplifies androgen biosynthesis, and impairs folliculogenesis (,).3Subakathulla Sumayyah (2026)Redox-endocrine triad in PCOS: can vitamin D, myo-inositol, and melatonin synergize as bioactive cocktails?
Myo-Inositol Sleep Quality Randomized TrialLow-dose variants of OCPs have been observed with an increased risk of myocardial infarction and cardiovascular arterial disease ().3Subakathulla Sumayyah (2026)Redox-endocrine triad in PCOS: can vitamin D, myo-inositol, and melatonin synergize as bioactive cocktails?
Myo-Inositol Sleep Quality Randomized Trial1 2 3 4 5 Polycystic ovary syndrome (PCOS) represents one of the most complex endocrine-metabolic disorders affecting women of reproductive age, characterized by a collection of reproductive, metabolic, and psychological manifestations (,).3Subakathulla Sumayyah (2026)Redox-endocrine triad in PCOS: can vitamin D, myo-inositol, and melatonin synergize as bioactive cocktails?
Myo-Inositol Sleep Quality Randomized TrialConclusions and outlook Myo-inositol has a more acceptable safety profile than metformin, which is known to be associated with gastrointestinal adverse effects and, in rare cases, lactic acidosis.4Russo M (2025)Metformin and Myo-Inositol: A Comparative Analysis.
Myo-Inositol Sleep Quality Randomized TrialBackground In the field of polycystic ovary syndrome (PCOS), metformin and myo-inositol are frequently employed to treat the endocrine-metabolic aspects of the condition.4Russo M (2025)Metformin and Myo-Inositol: A Comparative Analysis.
Myo-Inositol Sleep Quality Randomized TrialAccordingly, myo-inositol is sometimes considered as a nutraceutical alternative for metformin.4Russo M (2025)Metformin and Myo-Inositol: A Comparative Analysis.

Source documents

  1. Redox-endocrine triad in PCOS: can vitamin D, myo-inositol, and melatonin synergize as bioactive cocktails?
  2. Metformin and Myo-Inositol: A Comparative Analysis.