topicMulberry Blood Glucose Meta-Analysis
claimMMC administration in a rat model of type 2 diabetes mellitus (T2DM) significantly reduced blood glucose, insulin, and lipid levels.
evidence level3
citationChen Jia (2026)
sourceNew directions in mulberry leaf research for diabetes: a translational approach based on multi-component synergy
topicMulberry Blood Glucose Meta-Analysis
claimInfographic showing mulberry leaf mechanisms for controlling blood glucose: delayed glucose absorption in the small intestine, maintained insulin secretion in the pancreas, enhanced insulin sensitivity in peripheral tissues, and reduced hepatic glucose output with increased glycogen synthesis in the liver.
evidence level3
citationChen Jia (2026)
sourceNew directions in mulberry leaf research for diabetes: a translational approach based on multi-component synergy
topicMulberry Blood Glucose Meta-Analysis
claimAt the heart of this mechanism lies 1-DNJ, a unique alkaloid found in ML, which interferes with the intestinal step of the final digestion of carbohydrates by means of “competitive inhibition.” The 1-DNJ primarily inhibits two types of key digestive enzymes: α-glucosidase and α-amylase ().
evidence level3
citationChen Jia (2026)
sourceNew directions in mulberry leaf research for diabetes: a translational approach based on multi-component synergy
topicMulberry Blood Glucose Meta-Analysis
claim1 2 3 4 Diabetes mellitus (DM) is a common metabolic disease, the incidence of which is rapidly increasing worldwide and has become one of the major public health problems threatening human health ().
evidence level3
citationChen Jia (2026)
sourceNew directions in mulberry leaf research for diabetes: a translational approach based on multi-component synergy
topicMulberry Blood Glucose Meta-Analysis
claimThese factors collectively increase the risk of cardiovascular disease, diabetes, and cognitive impairment.
evidence level4
citationYu JT (2025)
sourceIntegrative Evidence on Mulberry Extract for Modulating Metabolic Risk Factors Associated with Vascular Dementia.
topicMulberry Blood Glucose Meta-Analysis
claimThis meta-analysis assessed the potential of mulberry extract as an adjunctive treatment for metabolic risk factors linked to vascular dementia.
evidence level4
citationYu JT (2025)
sourceIntegrative Evidence on Mulberry Extract for Modulating Metabolic Risk Factors Associated with Vascular Dementia.
topicMulberry Blood Glucose Meta-Analysis
claimThe pooled results indicated that mulberry supplementation improved blood sugar control and lowered total cholesterol, low-density lipoprotein cholesterol (LDL), triglycerides, fasting blood glucose, glycosylated hemoglobin (HbA1c), homeostasis model assessment for insulin resistance (HOMA-IR), and inflammatory markers.
evidence level4
citationYu JT (2025)
sourceIntegrative Evidence on Mulberry Extract for Modulating Metabolic Risk Factors Associated with Vascular Dementia.
topicMulberry Blood Glucose Meta-Analysis
claimMetabolic syndrome refers to a group of conditions that commonly occur together, including abdominal obesity, high blood pressure, elevated blood sugar, high triglyceride levels, and low high-density lipoprotein cholesterol (HDL).
evidence level4
citationYu JT (2025)
sourceIntegrative Evidence on Mulberry Extract for Modulating Metabolic Risk Factors Associated with Vascular Dementia.