Structured evidence table for Milk Thistle Liver Health Meta-Analysis, generated from 2 reusable source documents in the Migaku knowledge base.
| topic | claim | evidence level | citation | source |
|---|---|---|---|---|
| Milk Thistle Liver Health Meta-Analysis | Conclusion Silymarin combined with lifestyle modifications is a safe and effective treatment option for reducing and normalizing liver enzyme levels in patients with NAFLD and associated metabolic syndrome. | 4 | Sukeepaisarnjaroen W (2026) | Effectiveness of silymarin with lifestyle intervention in NAFLD and metabolic syndrome: a prospective single-arm study. |
| Milk Thistle Liver Health Meta-Analysis | Background Non-alcoholic fatty liver disease (NAFLD) has now become a major global health concern. | 4 | Sukeepaisarnjaroen W (2026) | Effectiveness of silymarin with lifestyle intervention in NAFLD and metabolic syndrome: a prospective single-arm study. |
| Milk Thistle Liver Health Meta-Analysis | Lifestyle modifications are the first line of treatment; however, their effectiveness is often limited. | 4 | Sukeepaisarnjaroen W (2026) | Effectiveness of silymarin with lifestyle intervention in NAFLD and metabolic syndrome: a prospective single-arm study. |
| Milk Thistle Liver Health Meta-Analysis | Recent mechanistic evidence suggests that these pathways converge on mitochondrial protection and the regulation of oxidative phosphorylation, contributing to their dual hepatocellular and neuroprotective actions (). | 4 | Sayyad Mahewish (2025) | Silymarin as a phytopharmaceutical agent: advances in mechanistic insights, formulation strategies, and pre-clinical applications |
| Milk Thistle Liver Health Meta-Analysis | Increased production of key antioxidant and detoxification enzymes and cofactors. | 4 | Sayyad Mahewish (2025) | Silymarin as a phytopharmaceutical agent: advances in mechanistic insights, formulation strategies, and pre-clinical applications |
| Milk Thistle Liver Health Meta-Analysis | (2021) 7 Bone Bone Mineralization Stimulation Undefined specific molecular pathways; experimental evidence suggests direct effect. | 4 | Sayyad Mahewish (2025) | Silymarin as a phytopharmaceutical agent: advances in mechanistic insights, formulation strategies, and pre-clinical applications |
| Milk Thistle Liver Health Meta-Analysis | Among them, silymarin, a phytocomplex of(milk thistle), has emerged as one of the most mechanistically characterised botanical agents in hepatoprotective and neuroprotective therapy. | 4 | Sayyad Mahewish (2025) | Silymarin as a phytopharmaceutical agent: advances in mechanistic insights, formulation strategies, and pre-clinical applications |
Source documents