evidence table
Milk Thistle Liver Disease Meta-Analysis Evidence Table
Structured evidence table for Milk Thistle Liver Disease Meta-Analysis, generated from 2 reusable source documents in the Migaku knowledge base.
| topic | claim | evidence level | citation | source |
|---|---|---|---|---|
| Milk Thistle Liver Disease Meta-Analysis | Silymarin, extracted from the seeds of Silybum marianum (milk thistle), has been utilised in traditional medicine for many years and is recognised for its neuroprotective and hepatoprotective properties. | 4 | Sayyad M (2025) | Silymarin as a phytopharmaceutical agent: advances in mechanistic insights, formulation strategies, and pre-clinical applications. |
| Milk Thistle Liver Disease Meta-Analysis | Existing research reveals that silymarin has potent antioxidant and anti-inflammatory effects, coupled with anti-fibrotic, anti-carcinogenic, neuro-regenerative, and immunomodulatory actions, and has broad therapeutic relevance in both neurological and hepatic disorders, albeit with the drawback of low solubility. | 4 | Sayyad M (2025) | Silymarin as a phytopharmaceutical agent: advances in mechanistic insights, formulation strategies, and pre-clinical applications. |
| Milk Thistle Liver Disease Meta-Analysis | This evidence is on four FDA-recognized (Food and Drug Administration) medicinal plants. | 4 | Burdan O (2025) | Mechanistic Insights into the Anti-Inflammatory and Anti-Proliferative Effects of Selected Medicinal Plants in Endometriosis. |
| Milk Thistle Liver Disease Meta-Analysis | Endometriosis involves oestrogen-dependent chronic inflammation and the abnormal proliferation of ectopic endometrial tissue. | 4 | Burdan O (2025) | Mechanistic Insights into the Anti-Inflammatory and Anti-Proliferative Effects of Selected Medicinal Plants in Endometriosis. |
| Milk Thistle Liver Disease Meta-Analysis | Conventional hormonal therapies suppress systemic oestrogen, but do not fully address local oxidative and inflammatory signalling. | 4 | Burdan O (2025) | Mechanistic Insights into the Anti-Inflammatory and Anti-Proliferative Effects of Selected Medicinal Plants in Endometriosis. |
Source documents