topicMilk Thistle Fatigue Meta-Analysis
claimConclusion Silymarin combined with lifestyle modifications is a safe and effective treatment option for reducing and normalizing liver enzyme levels in patients with NAFLD and associated metabolic syndrome.
evidence level4
citationSukeepaisarnjaroen W (2026)
sourceEffectiveness of silymarin with lifestyle intervention in NAFLD and metabolic syndrome: a prospective single-arm study.
topicMilk Thistle Fatigue Meta-Analysis
claimBackground Non-alcoholic fatty liver disease (NAFLD) has now become a major global health concern.
evidence level4
citationSukeepaisarnjaroen W (2026)
sourceEffectiveness of silymarin with lifestyle intervention in NAFLD and metabolic syndrome: a prospective single-arm study.
topicMilk Thistle Fatigue Meta-Analysis
claimLifestyle modifications are the first line of treatment; however, their effectiveness is often limited.
evidence level4
citationSukeepaisarnjaroen W (2026)
sourceEffectiveness of silymarin with lifestyle intervention in NAFLD and metabolic syndrome: a prospective single-arm study.
topicMilk Thistle Fatigue Meta-Analysis
claimThis evidence is on four FDA-recognized (Food and Drug Administration) medicinal plants.
evidence level4
citationBurdan O (2025)
sourceMechanistic Insights into the Anti-Inflammatory and Anti-Proliferative Effects of Selected Medicinal Plants in Endometriosis.
topicMilk Thistle Fatigue Meta-Analysis
claimEndometriosis involves oestrogen-dependent chronic inflammation and the abnormal proliferation of ectopic endometrial tissue.
evidence level4
citationBurdan O (2025)
sourceMechanistic Insights into the Anti-Inflammatory and Anti-Proliferative Effects of Selected Medicinal Plants in Endometriosis.
topicMilk Thistle Fatigue Meta-Analysis
claimConventional hormonal therapies suppress systemic oestrogen, but do not fully address local oxidative and inflammatory signalling.
evidence level4
citationBurdan O (2025)
sourceMechanistic Insights into the Anti-Inflammatory and Anti-Proliferative Effects of Selected Medicinal Plants in Endometriosis.