topicMarine Collagen Skin Elasticity Randomized Trial
claim1 The phenomenon of aging is inescapable and is characterized by multiple clinical manifestations, including wrinkles, reduced skin density, loss of elasticity, xerosis, uneven pigmentation, telangiectasia, sagging, and impaired wound healing.
evidence level1
citationNukaly Houriah Y. (2026)
sourceOral and topical peptides for skin aging: systematic review and meta-analysis of randomized controlled trials
topicMarine Collagen Skin Elasticity Randomized Trial
claimPeptides act as signaling molecules that mimic the body's natural processes to stimulate collagen synthesis, as well as enhancing other extracellular matrix (ECM) components such as hyaluronic acid by fibroblasts, help to rebuild the skin's structural integrity, resulting in improved skin texture, reduced wrinkles, and increased elasticity and hydration.
evidence level1
citationNukaly Houriah Y. (2026)
sourceOral and topical peptides for skin aging: systematic review and meta-analysis of randomized controlled trials
topicMarine Collagen Skin Elasticity Randomized Trial
claim2 4 A prime example of the efficacy of oral supplements is hydrolyzed collagen peptides, that significantly improved skin hydration, elasticity, roughness, and density in a randomized, placebo-controlled trial ().
evidence level1
citationNukaly Houriah Y. (2026)
sourceOral and topical peptides for skin aging: systematic review and meta-analysis of randomized controlled trials
topicMarine Collagen Skin Elasticity Randomized Trial
claimp p Oral polypeptides significantly improve skin hydration (Mean Difference [MD]: 5.80,< 0.01) and wrinkle reduction (MD: 0.35,= 0.05), outperforming topical formulations.
evidence level1
citationNukaly Houriah Y. (2026)
sourceOral and topical peptides for skin aging: systematic review and meta-analysis of randomized controlled trials
topicMarine Collagen Skin Elasticity Randomized Trial
claimCollagen, along with antioxidants such as curcumin and glutathione, have gained increased utilization/awareness in recent years, providing dermal health benefits especially in women who experience declining or loss of estrogen with aging.
evidence level4
citationArbex Priscila (2026)
sourceCollagen, Curcumin, and Glutathione to Enhance Dermal Health in Aging Women with Declining Estrogen Levels —A Narrative Review
topicMarine Collagen Skin Elasticity Randomized Trial
claimThe evidence of oral collagen as a nutraceutical is robust for improving several aspects of dermal health.
evidence level4
citationArbex Priscila (2026)
sourceCollagen, Curcumin, and Glutathione to Enhance Dermal Health in Aging Women with Declining Estrogen Levels —A Narrative Review
topicMarine Collagen Skin Elasticity Randomized Trial
claimFor example, the epidermis is without a blood supply and does not have the same circulation and nutrient delivery found in the dermis [–].
evidence level4
citationArbex Priscila (2026)
sourceCollagen, Curcumin, and Glutathione to Enhance Dermal Health in Aging Women with Declining Estrogen Levels —A Narrative Review
topicMarine Collagen Skin Elasticity Randomized Trial
claimThe present narrative review is an extension of a larger project that covered polyphenols and phytoestrogens.
evidence level4
citationArbex Priscila (2026)
sourceCollagen, Curcumin, and Glutathione to Enhance Dermal Health in Aging Women with Declining Estrogen Levels —A Narrative Review