Structured evidence table for Marine Collagen Skin Elasticity Meta-Analysis, generated from 2 reusable source documents in the Migaku knowledge base.
| topic | claim | evidence level | citation | source |
|---|---|---|---|---|
| Marine Collagen Skin Elasticity Meta-Analysis | The vascularity POSAS score (observer component) decreased from 7 at baseline to 3 at T6; the thickness and flexibility scores improved from 5 to 2 and from 7 to 3, respectively. | 4 | Fraone N (2026) | Stand-Alone Carboxytherapy Followed by Consolidation with Oral Hydrolyzed Marine Collagen Fragments: A Potential Sequential Bioregenerative Strategy for Hypertrophic Scars: A Case Report. |
| Marine Collagen Skin Elasticity Meta-Analysis | Conclusion Stand-alone carboxytherapy again appears to be an effective option for hypertrophic, structurally abnormal scars. | 4 | Fraone N (2026) | Stand-Alone Carboxytherapy Followed by Consolidation with Oral Hydrolyzed Marine Collagen Fragments: A Potential Sequential Bioregenerative Strategy for Hypertrophic Scars: A Case Report. |
| Marine Collagen Skin Elasticity Meta-Analysis | Introduction Carboxytherapy, via the Bohr effect, a denser dermal environment, and preserved fibroblast function, along with oral administration of bioactive marine collagen fragments that target fibroblasts, are regenerative strategies that could improve scar elasticity, thickness, and hydration. | 4 | Fraone N (2026) | Stand-Alone Carboxytherapy Followed by Consolidation with Oral Hydrolyzed Marine Collagen Fragments: A Potential Sequential Bioregenerative Strategy for Hypertrophic Scars: A Case Report. |
| Marine Collagen Skin Elasticity Meta-Analysis | Methods In March 2024, a 56-year-old woman began treatment of a large, hypertrophic, partially retracted post-surgical scar in the nasojugal area at the level of the right nasal wing. | 4 | Fraone N (2026) | Stand-Alone Carboxytherapy Followed by Consolidation with Oral Hydrolyzed Marine Collagen Fragments: A Potential Sequential Bioregenerative Strategy for Hypertrophic Scars: A Case Report. |
| Marine Collagen Skin Elasticity Meta-Analysis | A representative disorder associated with collagen type V deficiency is Ehlers‐Danlos syndrome (EDS), a congenital disease that primarily affects the connective tissue of the skin and joints. | 4 | Kim Ye Hyang (2025) | The Human‐Like Collagen Alpha‐1 Type V Peptides Strengthen the Dermal Fiber Network and Improve the Regeneration Ability of Cells |
| Marine Collagen Skin Elasticity Meta-Analysis | These changes, including collagen degradation and reduced collagen biosynthesis, result in aberrant collagen homeostasis and net collagen deficiency [,,,,]. | 4 | Kim Ye Hyang (2025) | The Human‐Like Collagen Alpha‐1 Type V Peptides Strengthen the Dermal Fiber Network and Improve the Regeneration Ability of Cells |
| Marine Collagen Skin Elasticity Meta-Analysis | Therefore, the present study aimed to investigate whether human‐like collagen alpha‐1 type V peptides (hCOLVp) could enhance not only the synthesis of collagen and barrier‐associated proteins but also contribute to the structural organization of the dermal matrix. | 4 | Kim Ye Hyang (2025) | The Human‐Like Collagen Alpha‐1 Type V Peptides Strengthen the Dermal Fiber Network and Improve the Regeneration Ability of Cells |
| Marine Collagen Skin Elasticity Meta-Analysis | 1 2 3 4 5 The skin, the body's outermost organ, serves as an important barrier that protects against the external environment and provides resistance to repetitive mechanical stress while maintaining flexibility for movement. | 4 | Kim Ye Hyang (2025) | The Human‐Like Collagen Alpha‐1 Type V Peptides Strengthen the Dermal Fiber Network and Improve the Regeneration Ability of Cells |
Source documents