evidence table

Magnesium Threonate Memory Randomized Trial Evidence Table

Name: Magnesium Threonate Memory Randomized Trial Evidence Table
Creator: Migaku
License: https://creativecommons.org/licenses/by/4.0/

Structured evidence table for Magnesium Threonate Memory Randomized Trial, generated from 2 reusable source documents in the Migaku knowledge base.

topic	claim	evidence level	citation	source
Magnesium Threonate Memory Randomized Trial	Results Compared to the placebo, Magtein ® was associated with greater improvements in overall cognitive performance as measured by the NIH Total Cognition Composite ( p = 0.043), with larger treatment effects on working and episodic memory.	2	Lopresti AL (2026)	The effects of magnesium L-threonate (Magtein<sup>®</sup>) on cognitive performance and sleep quality in adults: a randomised, double-blind, placebo-controlled trial.
Magnesium Threonate Memory Randomized Trial	Based on data from the sleep tracking ring, there were no group differences in sleep outcomes, although there was a greater reduction in HR ( p = 0.030) and an increase in HRV ( p = 0.036), a physiological marker of stress reduction and improved autonomic balance.	2	Lopresti AL (2026)	The effects of magnesium L-threonate (Magtein<sup>®</sup>) on cognitive performance and sleep quality in adults: a randomised, double-blind, placebo-controlled trial.
Magnesium Threonate Memory Randomized Trial	Conclusion The results from this study suggest Magtein ® supplementation for 6 weeks improves overall cognition, cognitive age, working memory, reaction time, HR, HRV, and some subjective, but not objective measures of sleep in healthy adults with self-reported dissatisfied sleep.	2	Lopresti AL (2026)	The effects of magnesium L-threonate (Magtein<sup>®</sup>) on cognitive performance and sleep quality in adults: a randomised, double-blind, placebo-controlled trial.
Magnesium Threonate Memory Randomized Trial	The purpose of this two-arm, 6-week, parallel-group, randomised, double-blind, placebo-controlled trial was to examine the effects of magnesium L-threonate (Magtein ® ) supplementation on cognitive performance, cognitive age, sleep quality, and selected physiological indicators in adults.	2	Lopresti AL (2026)	The effects of magnesium L-threonate (Magtein<sup>®</sup>) on cognitive performance and sleep quality in adults: a randomised, double-blind, placebo-controlled trial.
Magnesium Threonate Memory Randomized Trial	8 In particular, statins may indirectly affect neurodegenerative trajectories by improving cerebrovascular function and reducing vascular risk factors, which are increasingly appreciated as contributors to cognitive decline and mixed dementia phenotypes [].	3	Chiatto Luigi Maria (2026)	The Use of Statins in Parkinson's and Alzheimer's Disease: A 2021–2025 State‐of‐the‐Art Review of Clinical and Preclinical Evidence
Magnesium Threonate Memory Randomized Trial	9 10 Clinical evidence regarding the association between statin use and neurodegenerative outcomes has been heterogeneous and, in some cases, contradictory [].	3	Chiatto Luigi Maria (2026)	The Use of Statins in Parkinson's and Alzheimer's Disease: A 2021–2025 State‐of‐the‐Art Review of Clinical and Preclinical Evidence
Magnesium Threonate Memory Randomized Trial	Therefore, in this comprehensive narrative review, we synthesize and critically appraise preclinical and clinical evidence published between 2021 and 2025 on the use of statins in PD and AD.	3	Chiatto Luigi Maria (2026)	The Use of Statins in Parkinson's and Alzheimer's Disease: A 2021–2025 State‐of‐the‐Art Review of Clinical and Preclinical Evidence
Magnesium Threonate Memory Randomized Trial	1 1 2 Parkinson's disease (PD) and Alzheimer's disease (AD) represent the two most prevalent neurodegenerative disorders worldwide and constitute a rapidly escalating public health challenge in aging societies [].	3	Chiatto Luigi Maria (2026)	The Use of Statins in Parkinson's and Alzheimer's Disease: A 2021–2025 State‐of‐the‐Art Review of Clinical and Preclinical Evidence