topicMagnesium Pms Randomized Trial
claimMoreover, taking such drugs during Ramadan has been reported to increase the risk of cerebral venous thrombosis [], and psychological resistance remains a major global challenge [].
evidence level2
citationIimura Jun (2026)
sourceNovel dietary FemTech based on dietary reference intakes for premenstrual and menstrual disorders: a pilot open-label randomized controlled trial of dietary intervention
topicMagnesium Pms Randomized Trial
claimFor instance, Ahmadi reported that zinc supplementation reduced PMD symptoms [], and Tartagni reported the same for vitamin D [].
evidence level2
citationIimura Jun (2026)
sourceNovel dietary FemTech based on dietary reference intakes for premenstrual and menstrual disorders: a pilot open-label randomized controlled trial of dietary intervention
topicMagnesium Pms Randomized Trial
claimAs summarized by Carlini, there is insufficient evidence to recommend improvements through interventions with a single nutrient [].
evidence level2
citationIimura Jun (2026)
sourceNovel dietary FemTech based on dietary reference intakes for premenstrual and menstrual disorders: a pilot open-label randomized controlled trial of dietary intervention
topicMagnesium Pms Randomized Trial
claim1 2 3 4 5 Premenstrual disorder (PMD) is a serious issue for women across cultures, and is a comprehensive concept encompassing both physical and mental symptoms [].
evidence level2
citationIimura Jun (2026)
sourceNovel dietary FemTech based on dietary reference intakes for premenstrual and menstrual disorders: a pilot open-label randomized controlled trial of dietary intervention
topicMagnesium Pms Randomized Trial
claimPMD significantly impacts the overall health and well-being of women, contributing to higher levels of depression, anxiety, suicidal risk, impaired social and educational/work performance, and lower quality of life [,,–].
evidence level4
citationKrupa Anna Julia (2025)
sourceZinc, copper, and magnesium in premenstrual disorders: a narrative review
topicMagnesium Pms Randomized Trial
claimIt is estimated that 10% of women with PMDD have bipolar disorder, which poses a 7-fold higher risk compared to women without PMDD [].
evidence level4
citationKrupa Anna Julia (2025)
sourceZinc, copper, and magnesium in premenstrual disorders: a narrative review
topicMagnesium Pms Randomized Trial
claimEstrogens promote serotonergic transmission by upregulating the expression of the rate-limiting enzyme tryptophan hydroxylase (TPH), thereby increasing tryptophan levels (which is necessary for 5-HT synthesis) and downregulating the expression of the serotonin transporter (SERT), resulting in increased availability of 5-HT in the synaptic cleft [,].
evidence level4
citationKrupa Anna Julia (2025)
sourceZinc, copper, and magnesium in premenstrual disorders: a narrative review
topicMagnesium Pms Randomized Trial
claim1 1 2 3 1 1 4 Premenstrual symptoms refer to both psychological and somatic distress that present in the luteal phase of the menstrual cycle [].
evidence level4
citationKrupa Anna Julia (2025)
sourceZinc, copper, and magnesium in premenstrual disorders: a narrative review