topicMagnesium Blood Glucose Randomized Trial
claimPurpose Pre-diabetes significantly increases the risk of type 2 diabetes and cardiovascular disease.
evidence level2
citationYang J (2026)
sourceOral magnesium supplementation improves glycemic control in older Chinese adults with pre-diabetes and hypomagnesemia: a randomized controlled trial.
topicMagnesium Blood Glucose Randomized Trial
claimHowever, evidence for the efficacy of magnesium supplementation in pre-diabetes, especially in older adults with hypomagnesemia, remains limited and inconclusive.
evidence level2
citationYang J (2026)
sourceOral magnesium supplementation improves glycemic control in older Chinese adults with pre-diabetes and hypomagnesemia: a randomized controlled trial.
topicMagnesium Blood Glucose Randomized Trial
claimConclusion In older adults with pre-diabetes and hypomagnesemia, magnesium supplementation effectively corrected magnesium deficiency and reduced FPG, but did not improve other glycemic indices including HbA1c or insulin resistance.
evidence level2
citationYang J (2026)
sourceOral magnesium supplementation improves glycemic control in older Chinese adults with pre-diabetes and hypomagnesemia: a randomized controlled trial.
topicMagnesium Blood Glucose Randomized Trial
claimAlthough Mg is frequently discussed as an analgesic supplement, emerging evidence suggests that it acts as a neurovascular-metabolic modulator.
evidence level4
citationYoon Y (2026)
sourceMagnesium at the Neurovascular Interface: A Narrative Review of Atherosclerosis, Peripheral Arterial Disease, and Neuropathic Pain.
topicMagnesium Blood Glucose Randomized Trial
claimLow magnesium status has been associated with endothelial dysfunction, atherosclerotic burden, impaired microcirculatory function, and overlapping ischemic and neuropathic pain phenotypes, although direct causal clinical evidence remains limited.
evidence level4
citationYoon Y (2026)
sourceMagnesium at the Neurovascular Interface: A Narrative Review of Atherosclerosis, Peripheral Arterial Disease, and Neuropathic Pain.
topicMagnesium Blood Glucose Randomized Trial
claimThe evidence is strongest for mechanistic vascular and neuropathic pathways, whereas direct clinical evidence for magnesium supplementation in PAD-related ischemic limb pain remains limited.
evidence level4
citationYoon Y (2026)
sourceMagnesium at the Neurovascular Interface: A Narrative Review of Atherosclerosis, Peripheral Arterial Disease, and Neuropathic Pain.
topicMagnesium Blood Glucose Randomized Trial
claimMagnesium (Mg) is an essential divalent cation involved in more than 600 enzymatic reactions and plays a fundamental role in vascular, metabolic, and neural homeostasis.
evidence level4
citationYoon Y (2026)
sourceMagnesium at the Neurovascular Interface: A Narrative Review of Atherosclerosis, Peripheral Arterial Disease, and Neuropathic Pain.