Structured evidence table for Maca Stress Meta-Analysis, generated from 2 reusable source documents in the Migaku knowledge base.
| topic | claim | evidence level | citation | source |
|---|---|---|---|---|
| Maca Stress Meta-Analysis | In general, risk of bias in selective reporting and incomplete data were low, and bias regarding inclusion of intention-to-treat analysis was low to moderate. | 1 | Ho Chao-Yen (2026) | Herbal dietary supplements for erectile dysfunction: A systematic review and meta-analysis of randomized-controlled trials |
| Maca Stress Meta-Analysis | The analysis revealed a pooled SMD (pSMD) = 1.20 (95 % confidence interval [CI]: 0.64 to 1.76), indicating that taking herbal dietary supplements was associated with a greater improvement in erectile function as compared to controls. | 1 | Ho Chao-Yen (2026) | Herbal dietary supplements for erectile dysfunction: A systematic review and meta-analysis of randomized-controlled trials |
| Maca Stress Meta-Analysis | Saffron (pSMD = 2.23, 95 % CI: 1.66 to 2.80) and ginseng (pSMD = 0.41, 95 % CI: 0.20 to 0.62) were each significantly associated with greater improvement in ED compared to that of controls, whereaswas shown to have positive effects on ED compared to controls, but the difference was not statistically significant (pSMD = 0.74, 95 % CI: −0.24 to 1.72). | 1 | Ho Chao-Yen (2026) | Herbal dietary supplements for erectile dysfunction: A systematic review and meta-analysis of randomized-controlled trials |
| Maca Stress Meta-Analysis | Incidence of ED is reported to increase with increasing age.An estimated 8.3 % of insured men in the United States have been diagnosed with ED, translating to approximately 10.3 million men seeking care for this condition as of 2022. | 1 | Ho Chao-Yen (2026) | Herbal dietary supplements for erectile dysfunction: A systematic review and meta-analysis of randomized-controlled trials |
| Maca Stress Meta-Analysis | Under normal conditions, it is sequestered in the cytoplasm by Kelch-like ECH-associated protein 1 (Keap1), which targets it for degradation []. | 4 | Cipriano Giovanni Luca (2026) | Phytochemical and Fungal Bioactive Compounds in the “Brain Health Triad”: A Narrative Review on Neurostimulating, Neurotrophic, and Neuroprotective Synergy |
| Maca Stress Meta-Analysis | The following subsections provide a detailed analysis of the molecular profiles and clinical evidence for these three primary bioactives. | 4 | Cipriano Giovanni Luca (2026) | Phytochemical and Fungal Bioactive Compounds in the “Brain Health Triad”: A Narrative Review on Neurostimulating, Neurotrophic, and Neuroprotective Synergy |
| Maca Stress Meta-Analysis | In elderly patients with mild cognitive impairment (MCI), 16 weeks of Lion’s Mane supplementation significantly improved cognitive scores, with a subsequent decline observed once supplementation ceased, emphasizing its role in maintaining functional neural connectivity []. | 4 | Cipriano Giovanni Luca (2026) | Phytochemical and Fungal Bioactive Compounds in the “Brain Health Triad”: A Narrative Review on Neurostimulating, Neurotrophic, and Neuroprotective Synergy |
| Maca Stress Meta-Analysis | 1 2 3 4 5 6 The global increase in life expectancy has led to a parallel rise in the prevalence of neurodegenerative diseases and age-related cognitive decline [,], establishing brain health as a paramount priority in contemporary biomedical research. | 4 | Cipriano Giovanni Luca (2026) | Phytochemical and Fungal Bioactive Compounds in the “Brain Health Triad”: A Narrative Review on Neurostimulating, Neurotrophic, and Neuroprotective Synergy |
Source documents