topicLysine Exercise Recovery Randomized Trial
claimPlasma insulin concentrations increased following protein ingestion and were higher in the protein groups compared with PLA (time × treatment effect:< 0.001).
evidence level2
citationvan Lieshout Glenn AA (2025)
sourceMilk Protein Glycation Compromises Postprandial Lysine Bioavailability but does not Modulate Postprandial Muscle Protein Synthesis Rates In Vivo in Males: A Double-blind, Randomized Parallel Trial ☆
topicLysine Exercise Recovery Randomized Trial
claimIn contrast, when lysine was excluded from the EAAs, plasma EAA-Lys concentrations for HIGH-GLYC were slightly higher compared with LOW-GLYC between 90 and 120 min (≤ 0.018 for both timepoints,E), but this did not result in a different iAUC between the protein treatments over the full postprandial period (= 1.00,F).
evidence level2
citationvan Lieshout Glenn AA (2025)
sourceMilk Protein Glycation Compromises Postprandial Lysine Bioavailability but does not Modulate Postprandial Muscle Protein Synthesis Rates In Vivo in Males: A Double-blind, Randomized Parallel Trial ☆
topicLysine Exercise Recovery Randomized Trial
claimAs a result, peak lysine concentrations were 28% lower following ingestion of HIGH-GLYC compared with LOW-GLYC (191 ± 23 vs 266 ± 47 μmol · L, respectively,< 0.001).
evidence level2
citationvan Lieshout Glenn AA (2025)
sourceMilk Protein Glycation Compromises Postprandial Lysine Bioavailability but does not Modulate Postprandial Muscle Protein Synthesis Rates In Vivo in Males: A Double-blind, Randomized Parallel Trial ☆
topicLysine Exercise Recovery Randomized Trial
claim1 2 2 [3] [4] [5] [6] [7] [8] [9] 10 10 [11] [12] [13] 14 15 16 8 WHO Muscle is a highly adaptive organ that is constantly turning over, i.e., muscle proteins are continually synthesized and degraded.
evidence level2
citationvan Lieshout Glenn AA (2025)
sourceMilk Protein Glycation Compromises Postprandial Lysine Bioavailability but does not Modulate Postprandial Muscle Protein Synthesis Rates In Vivo in Males: A Double-blind, Randomized Parallel Trial ☆
topicLysine Exercise Recovery Randomized Trial
claimNo significant differences for total amino acid concentrations between RBC and plasma were found.
evidence level4
citationBorges N (2024)
sourceAmino acid distribution in blood following high-intensity interval exercise: a preliminary study.
topicLysine Exercise Recovery Randomized Trial
claimIndividual amino acid analyses showed significant interaction effects for alanine and α-aminoadipic acid (P < 0.05), with plasma alanine significantly increased from baseline across the recovery period (P < 0.001).
evidence level4
citationBorges N (2024)
sourceAmino acid distribution in blood following high-intensity interval exercise: a preliminary study.
topicLysine Exercise Recovery Randomized Trial
claimBlood fraction (group) effects showed greater concentrations of glycine, serine, asparagine, aspartic acid, glutamic acid, α-aminoadipic acid and ornithine in RBC, while greater concentrations of alanine, α-aminobutyric acid, valine, leucine, isoleucine, threonine, proline, phenylalanine, glutamine, tryptophan and cystine were found in plasma (P < 0.05).
evidence level4
citationBorges N (2024)
sourceAmino acid distribution in blood following high-intensity interval exercise: a preliminary study.
topicLysine Exercise Recovery Randomized Trial
claimThis study investigated the effect of high-intensity interval exercise on total and individual amino acid concentrations in red blood cells (RBCs) and plasma.
evidence level4
citationBorges N (2024)
sourceAmino acid distribution in blood following high-intensity interval exercise: a preliminary study.