Structured evidence table for Lutein Visual Performance Meta-Analysis, generated from 2 reusable source documents in the Migaku knowledge base.
| topic | claim | evidence level | citation | source |
|---|---|---|---|---|
| Lutein Visual Performance Meta-Analysis | However, these approaches require repeated invasive injections and are associated with considerable economic burden and procedural risks [,]. | 1 | Wang Wei-Xiang (2026) | From Supplements to Sight: Quantifying the Impact of Lutein and Carotenoid on Age‐Related Macular Degeneration—A Systematic Review and Meta‐Analysis of Randomized Controlled Trials |
| Lutein Visual Performance Meta-Analysis | Experimental and clinical studies have suggested that increased macular pigment levels may support visual performance and potentially attenuate AMD progression [–]. | 1 | Wang Wei-Xiang (2026) | From Supplements to Sight: Quantifying the Impact of Lutein and Carotenoid on Age‐Related Macular Degeneration—A Systematic Review and Meta‐Analysis of Randomized Controlled Trials |
| Lutein Visual Performance Meta-Analysis | Some findings from the Age‐Related Eye Disease Study 2 (AREDS2) indicated that lutein and zeaxanthin supplementation significantly reduced the risk of progression to late‐stage AMD []. | 1 | Wang Wei-Xiang (2026) | From Supplements to Sight: Quantifying the Impact of Lutein and Carotenoid on Age‐Related Macular Degeneration—A Systematic Review and Meta‐Analysis of Randomized Controlled Trials |
| Lutein Visual Performance Meta-Analysis | 1 2 3 4 5 6 7 Age‐related macular degeneration (AMD) remains one of the leading causes of irreversible central vision loss among individuals over 65 years of age worldwide. | 1 | Wang Wei-Xiang (2026) | From Supplements to Sight: Quantifying the Impact of Lutein and Carotenoid on Age‐Related Macular Degeneration—A Systematic Review and Meta‐Analysis of Randomized Controlled Trials |
| Lutein Visual Performance Meta-Analysis | This narrative review critically summarizes the available evidence on how various natural bioactive compounds, such as carotenoids, polyphenols, flavonoids, omega-3 fatty acids and botanical extracts, can affect important molecular pathways associated with ocular degeneration. | 4 | De Silva S (2026) | Beneficial Effects of Natural Bioactive Compounds on Eye Health: A Narrative Review. |
| Lutein Visual Performance Meta-Analysis | Moreover, it offers a framework for a comparison of evidence between preclinical and clinical studies, as well as identifying current translational gaps, including limited bioavailability and a lack of long-term clinical trials, and suggesting future directions such as genotype-guided nutrition and microbiome-informed interventions. | 4 | De Silva S (2026) | Beneficial Effects of Natural Bioactive Compounds on Eye Health: A Narrative Review. |
| Lutein Visual Performance Meta-Analysis | Ocular diseases like age-related macular degeneration (AMD), diabetic retinopathy (DR), glaucoma and cataracts are major causes of visual impairment all over the world and are closely linked to oxidative stress, inflammation and mitochondrial dysfunction. | 4 | De Silva S (2026) | Beneficial Effects of Natural Bioactive Compounds on Eye Health: A Narrative Review. |
Source documents