topicLutein Supplementation Visual Performance Meta-Analysis
claimHowever, these approaches require repeated invasive injections and are associated with considerable economic burden and procedural risks [,].
evidence level1
citationWang Wei-Xiang (2026)
sourceFrom Supplements to Sight: Quantifying the Impact of Lutein and Carotenoid on Age‐Related Macular Degeneration—A Systematic Review and Meta‐Analysis of Randomized Controlled Trials
topicLutein Supplementation Visual Performance Meta-Analysis
claimExperimental and clinical studies have suggested that increased macular pigment levels may support visual performance and potentially attenuate AMD progression [–].
evidence level1
citationWang Wei-Xiang (2026)
sourceFrom Supplements to Sight: Quantifying the Impact of Lutein and Carotenoid on Age‐Related Macular Degeneration—A Systematic Review and Meta‐Analysis of Randomized Controlled Trials
topicLutein Supplementation Visual Performance Meta-Analysis
claimSome findings from the Age‐Related Eye Disease Study 2 (AREDS2) indicated that lutein and zeaxanthin supplementation significantly reduced the risk of progression to late‐stage AMD [].
evidence level1
citationWang Wei-Xiang (2026)
sourceFrom Supplements to Sight: Quantifying the Impact of Lutein and Carotenoid on Age‐Related Macular Degeneration—A Systematic Review and Meta‐Analysis of Randomized Controlled Trials
topicLutein Supplementation Visual Performance Meta-Analysis
claim1 2 3 4 5 6 7 Age‐related macular degeneration (AMD) remains one of the leading causes of irreversible central vision loss among individuals over 65 years of age worldwide.
evidence level1
citationWang Wei-Xiang (2026)
sourceFrom Supplements to Sight: Quantifying the Impact of Lutein and Carotenoid on Age‐Related Macular Degeneration—A Systematic Review and Meta‐Analysis of Randomized Controlled Trials
topicLutein Supplementation Visual Performance Meta-Analysis
claim1 2 3 5 6 7 8 9 More than two billion people are at risk of micronutrient deficiencies, which often involve multiple, rather than single, nutrients [,].
evidence level4
citationMuacevic Alexander (2026)
sourceA to Z of Health: An Evidence-Based Narrative Review of Multivitamin-Multimineral and Nutraceutical Supplementation
topicLutein Supplementation Visual Performance Meta-Analysis
claimThey are widely used to help individuals meet their daily nutrient requirements, support overall health, and address increased nutritional needs associated with pregnancy, aging, and illness.
evidence level4
citationMuacevic Alexander (2026)
sourceA to Z of Health: An Evidence-Based Narrative Review of Multivitamin-Multimineral and Nutraceutical Supplementation
topicLutein Supplementation Visual Performance Meta-Analysis
claimAccording to the National Health and Nutrition Examination Survey, MVM use in the USA increased from 35% in 1999-2000 [] to 49-52% between 2011 and 2014, with higher usage among women than men [-].
evidence level4
citationMuacevic Alexander (2026)
sourceA to Z of Health: An Evidence-Based Narrative Review of Multivitamin-Multimineral and Nutraceutical Supplementation
topicLutein Supplementation Visual Performance Meta-Analysis
claimThe most common deficiencies include vitamin A, folic acid, vitamin D, iron, iodine, and zinc, especially among children and women in low- and middle-income countries [-].
evidence level4
citationMuacevic Alexander (2026)
sourceA to Z of Health: An Evidence-Based Narrative Review of Multivitamin-Multimineral and Nutraceutical Supplementation