Lactoferrin Supplementation Acne Meta-Analysis Evidence Table

Structured evidence table for Lactoferrin Supplementation Acne Meta-Analysis, generated from 2 reusable source documents in the Migaku knowledge base.

topicclaimevidence levelcitationsource
Lactoferrin Supplementation Acne Meta-AnalysisCutibacterium acnes Propionibacterium acnes 6 7 The pathogenesis of acne is multifactorial, arising from the interplay of increased sebum production, abnormal follicular keratinization, colonization with(formerly), and inflammation with contributions from genetic, hormonal, and environmental factors [].1Warp Peyton V. (2026)Prebiotics, Probiotics, and Postbiotics for Acne Vulgaris: A Systematic Review
Lactoferrin Supplementation Acne Meta-AnalysisLimited studies of gut microbiota in patients with acne have identified overall reduced diversity, a higher Bacteroidetes:Firmicutes ratio, enrichment of Proteobacteria, depletion of Actinobacteria, and loss of beneficial genera, includingand[–].1Warp Peyton V. (2026)Prebiotics, Probiotics, and Postbiotics for Acne Vulgaris: A Systematic Review
Lactoferrin Supplementation Acne Meta-AnalysisSeveral studies had unclear risk in selective reporting and performance bias, though outcome data were typically transparent and comprehensive.1Warp Peyton V. (2026)Prebiotics, Probiotics, and Postbiotics for Acne Vulgaris: A Systematic Review
Lactoferrin Supplementation Acne Meta-AnalysisThe gut–skin axis and human microbiome likely play a role in the pathogenesis of acne vulgaris.1Warp Peyton V. (2026)Prebiotics, Probiotics, and Postbiotics for Acne Vulgaris: A Systematic Review
Lactoferrin Supplementation Acne Meta-AnalysisWe link mechanistic insights with clinical and preclinical evidence and uniquely map molecular functions to dermatologic and trichologic outcomes.4Kaplan N (2026)The Protective and Regenerative Potential of Lactoferrin in Hair and Skin Health.
Lactoferrin Supplementation Acne Meta-AnalysisLactoferrin is a naturally occurring bioactive glycoprotein that is part of the body's innate immune system and has essential roles in iron metabolism, microbial defense, inflammation regulation, and tissue repair.4Kaplan N (2026)The Protective and Regenerative Potential of Lactoferrin in Hair and Skin Health.
Lactoferrin Supplementation Acne Meta-AnalysisIt supports the natural regulation of iron bioavailability in skin and hair follicles, helping to reduce excess free-iron-driven oxidative stress while preserving levels of necessary iron for cellular functions.4Kaplan N (2026)The Protective and Regenerative Potential of Lactoferrin in Hair and Skin Health.

Source documents

  1. Prebiotics, Probiotics, and Postbiotics for Acne Vulgaris: A Systematic Review
  2. The Protective and Regenerative Potential of Lactoferrin in Hair and Skin Health.