Structured evidence table for Lactoferrin Sleep Randomized Trial, generated from 2 reusable source documents in the Migaku knowledge base.
| topic | claim | evidence level | citation | source |
|---|---|---|---|---|
| Lactoferrin Sleep Randomized Trial | 11 12 11 13 14 15 16 17 18 19 Since the beginning of the COVID-19 crisis, public interest in hygiene, immunity, and inflammation has increased. | 3 | Lesgards Jean-François (2026) | Whey Proteins and Immunity: Mechanisms Underlying Immune System Reinforcement and Protection Against Viral and Bacterial Infections |
| Lactoferrin Sleep Randomized Trial | Dairy intake, particularly low-fat products, has been associated with reduced COVID-19 severity and hospitalization [,]. | 3 | Lesgards Jean-François (2026) | Whey Proteins and Immunity: Mechanisms Underlying Immune System Reinforcement and Protection Against Viral and Bacterial Infections |
| Lactoferrin Sleep Randomized Trial | More broadly, diets rich in fruits, vegetables, and omega-3s, and low in processed foods, may reduce inflammation and infection risk [,,], whereas malnutrition and obesity impair immunity and increase COVID-19 severity []. | 3 | Lesgards Jean-François (2026) | Whey Proteins and Immunity: Mechanisms Underlying Immune System Reinforcement and Protection Against Viral and Bacterial Infections |
| Lactoferrin Sleep Randomized Trial | 1 The innate immune system provides rapid, nonspecific defense through barriers, cytokines, and cells such as macrophages, dendritic cells, and NK cells, while the adaptive system generates antigen-specific and long-lasting protection via T and B lymphocytes, forming an integrated network essential for host defense []. | 3 | Lesgards Jean-François (2026) | Whey Proteins and Immunity: Mechanisms Underlying Immune System Reinforcement and Protection Against Viral and Bacterial Infections |
| Lactoferrin Sleep Randomized Trial | Women with IDWA may still experience fatigue, reduced concentration, impaired physical performance, and lower quality of life, and IDWA is estimated to affect approximately 15%-35% of women [,]. | 4 | Muacevic Alexander (2026) | Improving Iron Status Without Iron: Clinical Insights From Recombinant Human Lactoferrin Supplementation |
| Lactoferrin Sleep Randomized Trial | 13 14 15 15 Iron supplementation remains the standard treatment for iron deficiency; however, it is associated with many side effects, including gastrointestinal symptoms such as constipation, nausea, and abdominal discomfort [,]. | 4 | Muacevic Alexander (2026) | Improving Iron Status Without Iron: Clinical Insights From Recombinant Human Lactoferrin Supplementation |
| Lactoferrin Sleep Randomized Trial | As a result, alternative approaches that support iron metabolism have gained increasing interest. | 4 | Muacevic Alexander (2026) | Improving Iron Status Without Iron: Clinical Insights From Recombinant Human Lactoferrin Supplementation |
| Lactoferrin Sleep Randomized Trial | 1 2 3 4 5 5 Iron is an essential micronutrient needed for numerous biochemical pathways in the body. | 4 | Muacevic Alexander (2026) | Improving Iron Status Without Iron: Clinical Insights From Recombinant Human Lactoferrin Supplementation |
Source documents