Structured evidence table for Lactoferrin Skin Randomized Trial, generated from 2 reusable source documents in the Migaku knowledge base.
| topic | claim | evidence level | citation | source |
|---|---|---|---|---|
| Lactoferrin Skin Randomized Trial | It comprehensively consolidates the latest preclinical and clinical evidence, summarizes current research deficiencies and controversies, and proposes prospective research directions. | 3 | Zhang Hui (2026) | Lactoferrin as a Novel Therapeutic Agent in Dermatology: Current Evidence and Future Perspectives |
| Lactoferrin Skin Randomized Trial | This review aims to summarize current evidence regarding the molecular mechanisms, therapeutic applications, and translational potential of lactoferrin in major dermatological disorders, while identifying existing knowledge gaps and future research priorities. | 3 | Zhang Hui (2026) | Lactoferrin as a Novel Therapeutic Agent in Dermatology: Current Evidence and Future Perspectives |
| Lactoferrin Skin Randomized Trial | Finally, in the absence of human clinical evidence, the in vitro findings cannot be directly translated into clinical application. | 3 | Zhang Hui (2026) | Lactoferrin as a Novel Therapeutic Agent in Dermatology: Current Evidence and Future Perspectives |
| Lactoferrin Skin Randomized Trial | However, their clinical application is greatly restricted by inherent limitations, such as drug resistance, high recurrence rates, skin barrier damage, and undesirable systemic side effects,resulting in suboptimal long-term therapeutic outcomes and creating an urgent clinical demand for novel, safe, and multi-targeted therapeutic strategies for skin diseases. | 3 | Zhang Hui (2026) | Lactoferrin as a Novel Therapeutic Agent in Dermatology: Current Evidence and Future Perspectives |
| Lactoferrin Skin Randomized Trial | These peptides have been associated with immune regulation, anti-inflammatory, and antimicrobial properties [,], possibly modulating the gut microbiome [] and exhibiting systemic activity to mitigate microbial infections []. | 4 | Kaplan Nicole (2026) | The Protective and Regenerative Potential of Lactoferrin in Hair and Skin Health |
| Lactoferrin Skin Randomized Trial | In a clinical study, lactoferrin supplementation has been linked to a pronounced increase in circulating neutrophil precursors, and an associated reduction in TNF-α and IL-6 production []. | 4 | Kaplan Nicole (2026) | The Protective and Regenerative Potential of Lactoferrin in Hair and Skin Health |
| Lactoferrin Skin Randomized Trial | Although the mechanisms described here are associated with direct immune system regulation, lactoferrin also works through biochemical and cellular mechanisms that make it relevant for protection against environmental stressors such as pathogens and UV radiation [,], making it particularly relevant for hair and skin applications. | 4 | Kaplan Nicole (2026) | The Protective and Regenerative Potential of Lactoferrin in Hair and Skin Health |
| Lactoferrin Skin Randomized Trial | 1 1 2 3 4 1 4 Lactoferrin is a multifunctional, iron-binding glycoprotein that has protective and tissue healing capacities throughout the life of an organism []. | 4 | Kaplan Nicole (2026) | The Protective and Regenerative Potential of Lactoferrin in Hair and Skin Health |
Source documents