Lactoferrin Skin Health Meta-Analysis Evidence Table

Structured evidence table for Lactoferrin Skin Health Meta-Analysis, generated from 2 reusable source documents in the Migaku knowledge base.

topicclaimevidence levelcitationsource
Lactoferrin Skin Health Meta-Analysis11 12 11 13 14 15 16 17 18 19 Since the beginning of the COVID-19 crisis, public interest in hygiene, immunity, and inflammation has increased.3Lesgards Jean-François (2026)Whey Proteins and Immunity: Mechanisms Underlying Immune System Reinforcement and Protection Against Viral and Bacterial Infections
Lactoferrin Skin Health Meta-AnalysisDairy intake, particularly low-fat products, has been associated with reduced COVID-19 severity and hospitalization [,].3Lesgards Jean-François (2026)Whey Proteins and Immunity: Mechanisms Underlying Immune System Reinforcement and Protection Against Viral and Bacterial Infections
Lactoferrin Skin Health Meta-AnalysisMore broadly, diets rich in fruits, vegetables, and omega-3s, and low in processed foods, may reduce inflammation and infection risk [,,], whereas malnutrition and obesity impair immunity and increase COVID-19 severity [].3Lesgards Jean-François (2026)Whey Proteins and Immunity: Mechanisms Underlying Immune System Reinforcement and Protection Against Viral and Bacterial Infections
Lactoferrin Skin Health Meta-Analysis1 The innate immune system provides rapid, nonspecific defense through barriers, cytokines, and cells such as macrophages, dendritic cells, and NK cells, while the adaptive system generates antigen-specific and long-lasting protection via T and B lymphocytes, forming an integrated network essential for host defense [].3Lesgards Jean-François (2026)Whey Proteins and Immunity: Mechanisms Underlying Immune System Reinforcement and Protection Against Viral and Bacterial Infections
Lactoferrin Skin Health Meta-AnalysisThese peptides have been associated with immune regulation, anti-inflammatory, and antimicrobial properties [,], possibly modulating the gut microbiome [] and exhibiting systemic activity to mitigate microbial infections [].4Kaplan Nicole (2026)The Protective and Regenerative Potential of Lactoferrin in Hair and Skin Health
Lactoferrin Skin Health Meta-AnalysisIn a clinical study, lactoferrin supplementation has been linked to a pronounced increase in circulating neutrophil precursors, and an associated reduction in TNF-α and IL-6 production [].4Kaplan Nicole (2026)The Protective and Regenerative Potential of Lactoferrin in Hair and Skin Health
Lactoferrin Skin Health Meta-AnalysisAlthough the mechanisms described here are associated with direct immune system regulation, lactoferrin also works through biochemical and cellular mechanisms that make it relevant for protection against environmental stressors such as pathogens and UV radiation [,], making it particularly relevant for hair and skin applications.4Kaplan Nicole (2026)The Protective and Regenerative Potential of Lactoferrin in Hair and Skin Health
Lactoferrin Skin Health Meta-Analysis1 1 2 3 4 1 4 Lactoferrin is a multifunctional, iron-binding glycoprotein that has protective and tissue healing capacities throughout the life of an organism [].4Kaplan Nicole (2026)The Protective and Regenerative Potential of Lactoferrin in Hair and Skin Health
topicLactoferrin Skin Health Meta-Analysis
claim11 12 11 13 14 15 16 17 18 19 Since the beginning of the COVID-19 crisis, public interest in hygiene, immunity, and inflammation has increased.
evidence level3
citationLesgards Jean-François (2026)
sourceWhey Proteins and Immunity: Mechanisms Underlying Immune System Reinforcement and Protection Against Viral and Bacterial Infections
topicLactoferrin Skin Health Meta-Analysis
claimDairy intake, particularly low-fat products, has been associated with reduced COVID-19 severity and hospitalization [,].
evidence level3
citationLesgards Jean-François (2026)
sourceWhey Proteins and Immunity: Mechanisms Underlying Immune System Reinforcement and Protection Against Viral and Bacterial Infections
topicLactoferrin Skin Health Meta-Analysis
claimMore broadly, diets rich in fruits, vegetables, and omega-3s, and low in processed foods, may reduce inflammation and infection risk [,,], whereas malnutrition and obesity impair immunity and increase COVID-19 severity [].
evidence level3
citationLesgards Jean-François (2026)
sourceWhey Proteins and Immunity: Mechanisms Underlying Immune System Reinforcement and Protection Against Viral and Bacterial Infections
topicLactoferrin Skin Health Meta-Analysis
claim1 The innate immune system provides rapid, nonspecific defense through barriers, cytokines, and cells such as macrophages, dendritic cells, and NK cells, while the adaptive system generates antigen-specific and long-lasting protection via T and B lymphocytes, forming an integrated network essential for host defense [].
evidence level3
citationLesgards Jean-François (2026)
sourceWhey Proteins and Immunity: Mechanisms Underlying Immune System Reinforcement and Protection Against Viral and Bacterial Infections
topicLactoferrin Skin Health Meta-Analysis
claimThese peptides have been associated with immune regulation, anti-inflammatory, and antimicrobial properties [,], possibly modulating the gut microbiome [] and exhibiting systemic activity to mitigate microbial infections [].
evidence level4
citationKaplan Nicole (2026)
sourceThe Protective and Regenerative Potential of Lactoferrin in Hair and Skin Health
topicLactoferrin Skin Health Meta-Analysis
claimIn a clinical study, lactoferrin supplementation has been linked to a pronounced increase in circulating neutrophil precursors, and an associated reduction in TNF-α and IL-6 production [].
evidence level4
citationKaplan Nicole (2026)
sourceThe Protective and Regenerative Potential of Lactoferrin in Hair and Skin Health
topicLactoferrin Skin Health Meta-Analysis
claimAlthough the mechanisms described here are associated with direct immune system regulation, lactoferrin also works through biochemical and cellular mechanisms that make it relevant for protection against environmental stressors such as pathogens and UV radiation [,], making it particularly relevant for hair and skin applications.
evidence level4
citationKaplan Nicole (2026)
sourceThe Protective and Regenerative Potential of Lactoferrin in Hair and Skin Health
topicLactoferrin Skin Health Meta-Analysis
claim1 1 2 3 4 1 4 Lactoferrin is a multifunctional, iron-binding glycoprotein that has protective and tissue healing capacities throughout the life of an organism [].
evidence level4
citationKaplan Nicole (2026)
sourceThe Protective and Regenerative Potential of Lactoferrin in Hair and Skin Health

Source documents

  1. Whey Proteins and Immunity: Mechanisms Underlying Immune System Reinforcement and Protection Against Viral and Bacterial Infections
  2. The Protective and Regenerative Potential of Lactoferrin in Hair and Skin Health