Structured evidence table for Lactoferrin Immune Support Meta-Analysis, generated from 2 reusable source documents in the Migaku knowledge base.
| topic | claim | evidence level | citation | source |
|---|---|---|---|---|
| Lactoferrin Immune Support Meta-Analysis | We link mechanistic insights with clinical and preclinical evidence and uniquely map molecular functions to dermatologic and trichologic outcomes. | 4 | Kaplan N (2026) | The Protective and Regenerative Potential of Lactoferrin in Hair and Skin Health. |
| Lactoferrin Immune Support Meta-Analysis | Lactoferrin is a naturally occurring bioactive glycoprotein that is part of the body's innate immune system and has essential roles in iron metabolism, microbial defense, inflammation regulation, and tissue repair. | 4 | Kaplan N (2026) | The Protective and Regenerative Potential of Lactoferrin in Hair and Skin Health. |
| Lactoferrin Immune Support Meta-Analysis | It supports the natural regulation of iron bioavailability in skin and hair follicles, helping to reduce excess free-iron-driven oxidative stress while preserving levels of necessary iron for cellular functions. | 4 | Kaplan N (2026) | The Protective and Regenerative Potential of Lactoferrin in Hair and Skin Health. |
| Lactoferrin Immune Support Meta-Analysis | The PICOS question was: 'Are lactoferrin levels different between individuals with periodontitis and periodontally healthy controls, and are these levels associated with disease severity and established clinical periodontal indicators, supporting their role as diagnostic or prognostic biomarkers for periodontitis?'. | 4 | Patil GV (2026) | Role of lactoferrin in periodontal disease: A meta-analytical assessment of its reliability as a biomarker. |
| Lactoferrin Immune Support Meta-Analysis | Egger's regression test produced a t-statistic of -0.646 (P=0.529), reflecting a lack of significant evidence for publication bias. | 4 | Patil GV (2026) | Role of lactoferrin in periodontal disease: A meta-analytical assessment of its reliability as a biomarker. |
| Lactoferrin Immune Support Meta-Analysis | In conclusion, lactoferrin showed potential as a biomarker for periodontal disease, with elevated levels consistently linked to its presence and disease severity. | 4 | Patil GV (2026) | Role of lactoferrin in periodontal disease: A meta-analytical assessment of its reliability as a biomarker. |
| Lactoferrin Immune Support Meta-Analysis | The present systematic review and meta-analysis assessed the clinical utility of lactoferrin as a biomarker for periodontitis by evaluating its association with established periodontal parameters, including probing pocket depth (PPD), clinical attachment loss (CAL) and gingival index (GI). | 4 | Patil GV (2026) | Role of lactoferrin in periodontal disease: A meta-analytical assessment of its reliability as a biomarker. |
Source documents