topicL-Tyrosine Mood Randomized Trial
claimConclusion Our findings suggest that an 8-week supplementation with Portulaca oleracea can help alleviate depression and stress symptoms in patients with NAFLD.
evidence level2
citationMilkarizi N (2026)
sourceEffects of Hydro-Ethanolic Extract of <i>Portulaca oleracea</i> (Purslane) on Depression, Anxiety, and Stress Symptoms in Patients With Non-Alcoholic Fatty Liver Disease: A Randomized Double-Blind Controlled Trial.
topicL-Tyrosine Mood Randomized Trial
claimIntroduction Non-alcoholic fatty liver disease (NAFLD) is a prevalent chronic liver condition globally.
evidence level2
citationMilkarizi N (2026)
sourceEffects of Hydro-Ethanolic Extract of <i>Portulaca oleracea</i> (Purslane) on Depression, Anxiety, and Stress Symptoms in Patients With Non-Alcoholic Fatty Liver Disease: A Randomized Double-Blind Controlled Trial.
topicL-Tyrosine Mood Randomized Trial
claimPreliminary hypotheses suggest that Portulaca oleracea extract may improve mental health by modulating stress-related hormones.
evidence level2
citationMilkarizi N (2026)
sourceEffects of Hydro-Ethanolic Extract of <i>Portulaca oleracea</i> (Purslane) on Depression, Anxiety, and Stress Symptoms in Patients With Non-Alcoholic Fatty Liver Disease: A Randomized Double-Blind Controlled Trial.
topicL-Tyrosine Mood Randomized Trial
claimIncreasing evidence suggests that no single biomarker is likely to capture this complexity, and that integrative multi-omics approaches may provide a more clinically meaningful framework for precision psychiatry.
evidence level3
citationKowalczyk Mateusz (2026)
sourceAmino Acid–Fatty Acid Profile as a Novel Predictive Method in the Assessment of Diagnosis and Treatment Efficacy of Anxiety-Related Disorders and Mood Disorders
topicL-Tyrosine Mood Randomized Trial
claimThe co-occurrence of these conditions increases symptom severity, the risk of relapse, and reduces the likelihood of full remission.
evidence level3
citationKowalczyk Mateusz (2026)
sourceAmino Acid–Fatty Acid Profile as a Novel Predictive Method in the Assessment of Diagnosis and Treatment Efficacy of Anxiety-Related Disorders and Mood Disorders
topicL-Tyrosine Mood Randomized Trial
claimThis phenomenon is associated with an increased risk of hospitalization, suicide, and a marked rise in healthcare costs.
evidence level3
citationKowalczyk Mateusz (2026)
sourceAmino Acid–Fatty Acid Profile as a Novel Predictive Method in the Assessment of Diagnosis and Treatment Efficacy of Anxiety-Related Disorders and Mood Disorders
topicL-Tyrosine Mood Randomized Trial
claim1 2 Recurrent major depressive disorder and depressive episode (MDD; ICD-10: F32–F33) as well as generalized anxiety disorder (GAD; ICD-10: F41.1) are among the most prevalent and most burdensome psychiatric entities on a global scale.
evidence level3
citationKowalczyk Mateusz (2026)
sourceAmino Acid–Fatty Acid Profile as a Novel Predictive Method in the Assessment of Diagnosis and Treatment Efficacy of Anxiety-Related Disorders and Mood Disorders