evidence table
L-Theanine Stress Randomized Trial Evidence Table
Structured evidence table for L-Theanine Stress Randomized Trial, generated from 2 reusable source documents in the Migaku knowledge base.
| topic | claim | evidence level | citation | source |
|---|---|---|---|---|
| L-Theanine Stress Randomized Trial | Evidence regarding the acute effects of caffeine (CAF), L-theanine (TEA), and their combination remains inconsistent, particularly with respect to their combined influence on physical and cognitive performance in athletic populations. | 2 | Tuncer SY (2026) | Acute effects of combined and isolated caffeine and theanine supplementation on physical and cognitive performance in competitive athletes: a randomized, double-blind, placebo-controlled crossover study. |
| L-Theanine Stress Randomized Trial | Results Condition effects were found for leg strength ( p = 0.004, ηp 2 = 0.24) and back strength ( p = 0.008, ηp 2 = 0.19). | 2 | Tuncer SY (2026) | Acute effects of combined and isolated caffeine and theanine supplementation on physical and cognitive performance in competitive athletes: a randomized, double-blind, placebo-controlled crossover study. |
| L-Theanine Stress Randomized Trial | Additionally, no significant difference was found between the conditions in aerobic endurance, maximum isometric handgrip strength, and hand-eye coordination results. | 2 | Tuncer SY (2026) | Acute effects of combined and isolated caffeine and theanine supplementation on physical and cognitive performance in competitive athletes: a randomized, double-blind, placebo-controlled crossover study. |
| L-Theanine Stress Randomized Trial | Introduction Modern athletic performance is driven not only by physical capacity but also by rapid decision-making, attentional control, and visuomotor coordination. | 2 | Tuncer SY (2026) | Acute effects of combined and isolated caffeine and theanine supplementation on physical and cognitive performance in competitive athletes: a randomized, double-blind, placebo-controlled crossover study. |
| L-Theanine Stress Randomized Trial | Under normal conditions, it is sequestered in the cytoplasm by Kelch-like ECH-associated protein 1 (Keap1), which targets it for degradation []. | 4 | Cipriano Giovanni Luca (2026) | Phytochemical and Fungal Bioactive Compounds in the “Brain Health Triad”: A Narrative Review on Neurostimulating, Neurotrophic, and Neuroprotective Synergy |
| L-Theanine Stress Randomized Trial | The following subsections provide a detailed analysis of the molecular profiles and clinical evidence for these three primary bioactives. | 4 | Cipriano Giovanni Luca (2026) | Phytochemical and Fungal Bioactive Compounds in the “Brain Health Triad”: A Narrative Review on Neurostimulating, Neurotrophic, and Neuroprotective Synergy |
| L-Theanine Stress Randomized Trial | In elderly patients with mild cognitive impairment (MCI), 16 weeks of Lion’s Mane supplementation significantly improved cognitive scores, with a subsequent decline observed once supplementation ceased, emphasizing its role in maintaining functional neural connectivity []. | 4 | Cipriano Giovanni Luca (2026) | Phytochemical and Fungal Bioactive Compounds in the “Brain Health Triad”: A Narrative Review on Neurostimulating, Neurotrophic, and Neuroprotective Synergy |
| L-Theanine Stress Randomized Trial | 1 2 3 4 5 6 The global increase in life expectancy has led to a parallel rise in the prevalence of neurodegenerative diseases and age-related cognitive decline [,], establishing brain health as a paramount priority in contemporary biomedical research. | 4 | Cipriano Giovanni Luca (2026) | Phytochemical and Fungal Bioactive Compounds in the “Brain Health Triad”: A Narrative Review on Neurostimulating, Neurotrophic, and Neuroprotective Synergy |
Source documents
- Acute effects of combined and isolated caffeine and theanine supplementation on physical and cognitive performance in competitive athletes: a randomized, double-blind, placebo-controlled crossover study.
- Phytochemical and Fungal Bioactive Compounds in the “Brain Health Triad”: A Narrative Review on Neurostimulating, Neurotrophic, and Neuroprotective Synergy