topicL-Citrulline Cycling Performance Randomized Trial
claimBackground Nutrition plays a key role in training and athletic performance and dietary supplements can make a small, but potentially valuable, contribution to achieving peak athletic performance.
evidence level2
citationHarrington RN (2023)
sourceEffects of branched chain amino acids, l-citrulline, and alpha-glycerylphosphorylcholine supplementation on exercise performance in trained cyclists: a randomized crossover trial.
topicL-Citrulline Cycling Performance Randomized Trial
claimThis study is the first to investigate the effects of supplementation from the combination of BCAAs, L-citrulline, and A-GPC on exercise performance.
evidence level2
citationHarrington RN (2023)
sourceEffects of branched chain amino acids, l-citrulline, and alpha-glycerylphosphorylcholine supplementation on exercise performance in trained cyclists: a randomized crossover trial.
topicL-Citrulline Cycling Performance Randomized Trial
claimHeat production rises immediately during exercise and when it exceeds heat loss, there is a rise in body temperature that triggers thermoregulatory responses, such as increased skin blood flow and sweating to attenuate body temperature increases (Périard et al.).
evidence level4
citationCable Thomas G. (2024)
source7 days of L-citrulline supplementation does not improve running performance in the heat whilst in a hypohydrated state
topicL-Citrulline Cycling Performance Randomized Trial
claimDuring exercise in hot environments, conductive and convective heat loss capacity are reduced, making evaporative heat loss through sweating vital for thermoregulation (Dugas et al.).
evidence level4
citationCable Thomas G. (2024)
source7 days of L-citrulline supplementation does not improve running performance in the heat whilst in a hypohydrated state
topicL-Citrulline Cycling Performance Randomized Trial
claim2013 2019 2012 2013 2019 2019 2001 2019 2023 The increased sweat rate during exercise in hot environments further challenges thermoregulation as hypohydration is likely to accrue during prolonged endurance exercise, particularly whilst running (Dion et al.).
evidence level4
citationCable Thomas G. (2024)
source7 days of L-citrulline supplementation does not improve running performance in the heat whilst in a hypohydrated state
topicL-Citrulline Cycling Performance Randomized Trial
claim2021 2009 2014 Exercise increases metabolic rate (energy expenditure) with approximately 75% of this energy turnover appearing as heat production.
evidence level4
citationCable Thomas G. (2024)
source7 days of L-citrulline supplementation does not improve running performance in the heat whilst in a hypohydrated state