evidence table
Inositol PCOS Meta-Analysis Evidence Table
Structured evidence table for Inositol PCOS Meta-Analysis, generated from 2 reusable source documents in the Migaku knowledge base.
| topic | claim | evidence level | citation | source |
|---|---|---|---|---|
| Inositol PCOS Meta-Analysis | Objectives This umbrella review aimed to synthesize and appraise the evidence regarding the efficacy of inositol for Polycystic Ovary Syndrome (PCOS) by integrating meta-analyses of randomized controlled trials(RCTs), thereby assessing the robustness of the existing body of evidence. | 2 | Duan M (2026) | Effects of inositol in women with polycystic ovary syndrome: an umbrella review of meta-analyses from randomized controlled trials. |
| Inositol PCOS Meta-Analysis | GRADE assessment of 85 evidence items revealed no high-quality evidence; 18.9% were moderate, 40% low, and 41.1% very low quality. | 2 | Duan M (2026) | Effects of inositol in women with polycystic ovary syndrome: an umbrella review of meta-analyses from randomized controlled trials. |
| Inositol PCOS Meta-Analysis | Pooled analyses demonstrated that inositol significantly improved multiple outcomes compared to placebo/FA: it reduced serum luteinizing hormone (LH: MD -3.43 IU/L, 95% CI [-4.29, -2.56], P P P P P P = 0.03; ovulation rate: RR 2.75, 95% CI [1.71, 4.41], P Conclusion Inositol improves core PCOS manifestations. | 2 | Duan M (2026) | Effects of inositol in women with polycystic ovary syndrome: an umbrella review of meta-analyses from randomized controlled trials. |
| Inositol PCOS Meta-Analysis | Methods We searched four databases from inception to August 2025 for relevant RCT meta-analyses. | 2 | Duan M (2026) | Effects of inositol in women with polycystic ovary syndrome: an umbrella review of meta-analyses from randomized controlled trials. |
| Inositol PCOS Meta-Analysis | Conclusions and outlook Myo-inositol has a more acceptable safety profile than metformin, which is known to be associated with gastrointestinal adverse effects and, in rare cases, lactic acidosis. | 4 | Russo M (2025) | Metformin and Myo-Inositol: A Comparative Analysis. |
| Inositol PCOS Meta-Analysis | Background In the field of polycystic ovary syndrome (PCOS), metformin and myo-inositol are frequently employed to treat the endocrine-metabolic aspects of the condition. | 4 | Russo M (2025) | Metformin and Myo-Inositol: A Comparative Analysis. |
| Inositol PCOS Meta-Analysis | Accordingly, myo-inositol is sometimes considered as a nutraceutical alternative for metformin. | 4 | Russo M (2025) | Metformin and Myo-Inositol: A Comparative Analysis. |
Source documents