evidence table

Inositol Metabolic Health Meta-Analysis Evidence Table

Structured evidence table for Inositol Metabolic Health Meta-Analysis, generated from 2 reusable source documents in the Migaku knowledge base.

topicclaimevidence levelcitationsource
Inositol Metabolic Health Meta-AnalysisObjectives This umbrella review aimed to synthesize and appraise the evidence regarding the efficacy of inositol for Polycystic Ovary Syndrome (PCOS) by integrating meta-analyses of randomized controlled trials(RCTs), thereby assessing the robustness of the existing body of evidence.2Duan M (2026)Effects of inositol in women with polycystic ovary syndrome: an umbrella review of meta-analyses from randomized controlled trials.
Inositol Metabolic Health Meta-AnalysisGRADE assessment of 85 evidence items revealed no high-quality evidence; 18.9% were moderate, 40% low, and 41.1% very low quality.2Duan M (2026)Effects of inositol in women with polycystic ovary syndrome: an umbrella review of meta-analyses from randomized controlled trials.
Inositol Metabolic Health Meta-AnalysisPooled analyses demonstrated that inositol significantly improved multiple outcomes compared to placebo/FA: it reduced serum luteinizing hormone (LH: MD -3.43 IU/L, 95% CI [-4.29, -2.56], P P P P P P = 0.03; ovulation rate: RR 2.75, 95% CI [1.71, 4.41], P Conclusion Inositol improves core PCOS manifestations.2Duan M (2026)Effects of inositol in women with polycystic ovary syndrome: an umbrella review of meta-analyses from randomized controlled trials.
Inositol Metabolic Health Meta-AnalysisMethods We searched four databases from inception to August 2025 for relevant RCT meta-analyses.2Duan M (2026)Effects of inositol in women with polycystic ovary syndrome: an umbrella review of meta-analyses from randomized controlled trials.
Inositol Metabolic Health Meta-AnalysisIn addition to reproductive complications, PCOS is associated with several metabolic and systemic consequences (,).3Aydin Cil Mevra (2026)Two decades of nutrition research in polycystic ovary syndrome: emerging patterns and scientific output (2004–2024)
Inositol Metabolic Health Meta-AnalysisAt this point, PCOS is associated with an increased risk for developing reproductive, metabolic, cardiovascular, oncological, and psychological disturbances ().3Aydin Cil Mevra (2026)Two decades of nutrition research in polycystic ovary syndrome: emerging patterns and scientific output (2004–2024)
Inositol Metabolic Health Meta-AnalysisMeta-analyses have revealed that women with PCOS exhibit a greater prevalence of cardiometabolic risk factors that increase long-term healthcare costs, including metabolic syndrome, type 2 diabetes mellitus, dyslipidemia/hyperlipidemia, hypertension, and chronic low-grade inflammation (,).3Aydin Cil Mevra (2026)Two decades of nutrition research in polycystic ovary syndrome: emerging patterns and scientific output (2004–2024)
Inositol Metabolic Health Meta-Analysis1 2 3 2–4 5 6 Polycystic ovary syndrome (PCOS) is among the most prevalent endocrine disorders in women of reproductive age, affecting approximately one in five women.3Aydin Cil Mevra (2026)Two decades of nutrition research in polycystic ovary syndrome: emerging patterns and scientific output (2004–2024)
topicInositol Metabolic Health Meta-Analysis
claimObjectives This umbrella review aimed to synthesize and appraise the evidence regarding the efficacy of inositol for Polycystic Ovary Syndrome (PCOS) by integrating meta-analyses of randomized controlled trials(RCTs), thereby assessing the robustness of the existing body of evidence.
evidence level2
citationDuan M (2026)
sourceEffects of inositol in women with polycystic ovary syndrome: an umbrella review of meta-analyses from randomized controlled trials.
topicInositol Metabolic Health Meta-Analysis
claimGRADE assessment of 85 evidence items revealed no high-quality evidence; 18.9% were moderate, 40% low, and 41.1% very low quality.
evidence level2
citationDuan M (2026)
sourceEffects of inositol in women with polycystic ovary syndrome: an umbrella review of meta-analyses from randomized controlled trials.
topicInositol Metabolic Health Meta-Analysis
claimPooled analyses demonstrated that inositol significantly improved multiple outcomes compared to placebo/FA: it reduced serum luteinizing hormone (LH: MD -3.43 IU/L, 95% CI [-4.29, -2.56], P P P P P P = 0.03; ovulation rate: RR 2.75, 95% CI [1.71, 4.41], P Conclusion Inositol improves core PCOS manifestations.
evidence level2
citationDuan M (2026)
sourceEffects of inositol in women with polycystic ovary syndrome: an umbrella review of meta-analyses from randomized controlled trials.
topicInositol Metabolic Health Meta-Analysis
claimMethods We searched four databases from inception to August 2025 for relevant RCT meta-analyses.
evidence level2
citationDuan M (2026)
sourceEffects of inositol in women with polycystic ovary syndrome: an umbrella review of meta-analyses from randomized controlled trials.
topicInositol Metabolic Health Meta-Analysis
claimIn addition to reproductive complications, PCOS is associated with several metabolic and systemic consequences (,).
evidence level3
citationAydin Cil Mevra (2026)
sourceTwo decades of nutrition research in polycystic ovary syndrome: emerging patterns and scientific output (2004–2024)
topicInositol Metabolic Health Meta-Analysis
claimAt this point, PCOS is associated with an increased risk for developing reproductive, metabolic, cardiovascular, oncological, and psychological disturbances ().
evidence level3
citationAydin Cil Mevra (2026)
sourceTwo decades of nutrition research in polycystic ovary syndrome: emerging patterns and scientific output (2004–2024)
topicInositol Metabolic Health Meta-Analysis
claimMeta-analyses have revealed that women with PCOS exhibit a greater prevalence of cardiometabolic risk factors that increase long-term healthcare costs, including metabolic syndrome, type 2 diabetes mellitus, dyslipidemia/hyperlipidemia, hypertension, and chronic low-grade inflammation (,).
evidence level3
citationAydin Cil Mevra (2026)
sourceTwo decades of nutrition research in polycystic ovary syndrome: emerging patterns and scientific output (2004–2024)
topicInositol Metabolic Health Meta-Analysis
claim1 2 3 2–4 5 6 Polycystic ovary syndrome (PCOS) is among the most prevalent endocrine disorders in women of reproductive age, affecting approximately one in five women.
evidence level3
citationAydin Cil Mevra (2026)
sourceTwo decades of nutrition research in polycystic ovary syndrome: emerging patterns and scientific output (2004–2024)

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Source documents

  1. Effects of inositol in women with polycystic ovary syndrome: an umbrella review of meta-analyses from randomized controlled trials.
  2. Two decades of nutrition research in polycystic ovary syndrome: emerging patterns and scientific output (2004–2024)