evidence table
Inositol Insulin Resistance Meta-Analysis Evidence Table
Structured evidence table for Inositol Insulin Resistance Meta-Analysis, generated from 2 reusable source documents in the Migaku knowledge base.
| topic | claim | evidence level | citation | source |
|---|---|---|---|---|
| Inositol Insulin Resistance Meta-Analysis | Objectives This umbrella review aimed to synthesize and appraise the evidence regarding the efficacy of inositol for Polycystic Ovary Syndrome (PCOS) by integrating meta-analyses of randomized controlled trials(RCTs), thereby assessing the robustness of the existing body of evidence. | 2 | Duan M (2026) | Effects of inositol in women with polycystic ovary syndrome: an umbrella review of meta-analyses from randomized controlled trials. |
| Inositol Insulin Resistance Meta-Analysis | GRADE assessment of 85 evidence items revealed no high-quality evidence; 18.9% were moderate, 40% low, and 41.1% very low quality. | 2 | Duan M (2026) | Effects of inositol in women with polycystic ovary syndrome: an umbrella review of meta-analyses from randomized controlled trials. |
| Inositol Insulin Resistance Meta-Analysis | Pooled analyses demonstrated that inositol significantly improved multiple outcomes compared to placebo/FA: it reduced serum luteinizing hormone (LH: MD -3.43 IU/L, 95% CI [-4.29, -2.56], P P P P P P = 0.03; ovulation rate: RR 2.75, 95% CI [1.71, 4.41], P Conclusion Inositol improves core PCOS manifestations. | 2 | Duan M (2026) | Effects of inositol in women with polycystic ovary syndrome: an umbrella review of meta-analyses from randomized controlled trials. |
| Inositol Insulin Resistance Meta-Analysis | Methods We searched four databases from inception to August 2025 for relevant RCT meta-analyses. | 2 | Duan M (2026) | Effects of inositol in women with polycystic ovary syndrome: an umbrella review of meta-analyses from randomized controlled trials. |
| Inositol Insulin Resistance Meta-Analysis | It is often associated with hormonal imbalance, metabolic disturbances, and reproductive complications, which together contribute to an elevated risk of long-term cardiometabolic disorders. | 4 | Singnale P (2026) | Role of Functional Foods and Nutraceutical Compounds in Alleviating Polycystic Ovary Syndrome: A Narrative Review. |
| Inositol Insulin Resistance Meta-Analysis | To narratively synthesize mechanistic rationale and human clinical evidence on dietary seeds and selected nutraceuticals relevant to PCOS, with emphasis on metabolic and reproductive endpoints of interest to nutrition and obstetrics/gynecology practice. | 4 | Singnale P (2026) | Role of Functional Foods and Nutraceutical Compounds in Alleviating Polycystic Ovary Syndrome: A Narrative Review. |
| Inositol Insulin Resistance Meta-Analysis | Proposed "seed cycling" protocols have received attention, yet most clinical data are derived from mixed-seed supplementation studies or low-level evidence, such as case reports, and should be considered hypothesis-generating. | 4 | Singnale P (2026) | Role of Functional Foods and Nutraceutical Compounds in Alleviating Polycystic Ovary Syndrome: A Narrative Review. |
| Inositol Insulin Resistance Meta-Analysis | Polycystic ovary syndrome (PCOS) represents one of the most common endocrine disorders among women of reproductive age. | 4 | Singnale P (2026) | Role of Functional Foods and Nutraceutical Compounds in Alleviating Polycystic Ovary Syndrome: A Narrative Review. |
Source documents