Structured evidence table for Inositol Anxiety Meta-Analysis, generated from 2 reusable source documents in the Migaku knowledge base.
| topic | claim | evidence level | citation | source |
|---|---|---|---|---|
| Inositol Anxiety Meta-Analysis | Results Across AnxDs, tCho was significantly reduced in prefrontal cortex and across all cortical regions. | 1 | Maddock RJ (2025) | Transdiagnostic reduction in cortical choline-containing compounds in anxiety disorders: a <sup>1</sup>H-magnetic resonance spectroscopy meta-analysis. |
| Inositol Anxiety Meta-Analysis | NAA was unchanged in prefrontal cortex but reduced across all cortical regions (after exclusions). | 1 | Maddock RJ (2025) | Transdiagnostic reduction in cortical choline-containing compounds in anxiety disorders: a <sup>1</sup>H-magnetic resonance spectroscopy meta-analysis. |
| Inositol Anxiety Meta-Analysis | Discussion Reduced choline-containing compounds in cortical regions is a consistent, transdiagnostic abnormality in AnxDs. | 1 | Maddock RJ (2025) | Transdiagnostic reduction in cortical choline-containing compounds in anxiety disorders: a <sup>1</sup>H-magnetic resonance spectroscopy meta-analysis. |
| Inositol Anxiety Meta-Analysis | Background Anxiety disorders (AnxDs) are highly prevalent and often untreated or unresponsive to treatment. | 1 | Maddock RJ (2025) | Transdiagnostic reduction in cortical choline-containing compounds in anxiety disorders: a <sup>1</sup>H-magnetic resonance spectroscopy meta-analysis. |
| Inositol Anxiety Meta-Analysis | Conclusions and outlook Myo-inositol has a more acceptable safety profile than metformin, which is known to be associated with gastrointestinal adverse effects and, in rare cases, lactic acidosis. | 4 | Russo M (2025) | Metformin and Myo-Inositol: A Comparative Analysis. |
| Inositol Anxiety Meta-Analysis | Background In the field of polycystic ovary syndrome (PCOS), metformin and myo-inositol are frequently employed to treat the endocrine-metabolic aspects of the condition. | 4 | Russo M (2025) | Metformin and Myo-Inositol: A Comparative Analysis. |
| Inositol Anxiety Meta-Analysis | Accordingly, myo-inositol is sometimes considered as a nutraceutical alternative for metformin. | 4 | Russo M (2025) | Metformin and Myo-Inositol: A Comparative Analysis. |
Source documents