topicHydroxytyrosol Blood Pressure Meta-Analysis
claimDespite advances in reducing cardiovascular disease (CVD) incidence, CVD mortality has increased, emphasising the need for new preventive strategies.
evidence level2
citationLauwers S (2026)
sourceEvaluation of the effect of olive extracts on blood pressure and cardiovascular health markers in adults: Findings from a double-blind, placebo-controlled, randomised trial.
topicHydroxytyrosol Blood Pressure Meta-Analysis
claimHowever, this decrease was not found significantly different between the two groups.
evidence level2
citationLauwers S (2026)
sourceEvaluation of the effect of olive extracts on blood pressure and cardiovascular health markers in adults: Findings from a double-blind, placebo-controlled, randomised trial.
topicHydroxytyrosol Blood Pressure Meta-Analysis
claimPolyphenol-rich olive extracts have been proposed to lower blood pressure by reducing oxidative stress and enhancing nitric oxide production.
evidence level2
citationLauwers S (2026)
sourceEvaluation of the effect of olive extracts on blood pressure and cardiovascular health markers in adults: Findings from a double-blind, placebo-controlled, randomised trial.
topicHydroxytyrosol Blood Pressure Meta-Analysis
claimHowever, as deposits accumulate, the atherosclerotic plaque gradually enlarges, and the progressive inflammatory process in the vessel wall is associated with the development of unstable atherosclerotic lesions.
evidence level3
citationFilipek Agnieszka (2026)
sourceOleaceae plants: a source of metabolites with atheroprotective potential
topicHydroxytyrosol Blood Pressure Meta-Analysis
claimUnstable atherosclerotic plaques are characterized by increased vascularization, a thinner, rupture-prone fibrous cap, and an increased number of inflammatory cells.
evidence level3
citationFilipek Agnieszka (2026)
sourceOleaceae plants: a source of metabolites with atheroprotective potential
topicHydroxytyrosol Blood Pressure Meta-Analysis
claimTherefore, this paper aims to delve into the metabolites found in Oleaceae plants that demonstrate the ability to inhibit early and late atherosclerotic changes, elucidating the underlying mechanisms of action and highlighting their potential for future applications in cardiovascular disease prevention and treatment.
evidence level3
citationFilipek Agnieszka (2026)
sourceOleaceae plants: a source of metabolites with atheroprotective potential
topicHydroxytyrosol Blood Pressure Meta-Analysis
claimBjorkegren and Lusis, 2022 Chan and Ramji, 2022 Yu et al., 2024 Melamed and Goldhaber, 2014 Chung, 2016 Atherosclerosis, a chronic inflammatory disease affecting arterial walls, stands as a primary contributor to global morbidity and mortality, frequently culminating in myocardial infarction or ischemic stroke ().
evidence level3
citationFilipek Agnieszka (2026)
sourceOleaceae plants: a source of metabolites with atheroprotective potential