topicHyaluronic Skin Aging Meta-Analysis
claimIntroduction Skin aging, marked by wrinkles, volume loss, and reduced hydration, has driven growing interest in minimally invasive aesthetic treatments to restore skin quality and appearance.
evidence level1
citationMosteirin M (2026)
sourceEfficacy and Safety of Amino Acid-Enriched Hyaluronic Acid in Facial Rejuvenation: A Systematic Review and Meta-Analysis.
topicHyaluronic Skin Aging Meta-Analysis
claimA significant reduction in wrinkle severity was observed on WSRS following treatment (MD, 2.15; 95% CI, 2.00-2.30; p Conclusion Amino acid-enriched hyaluronic acid improves wrinkle severity, dermal thickness, and cell viability, enhancing overall skin aesthetics.
evidence level1
citationMosteirin M (2026)
sourceEfficacy and Safety of Amino Acid-Enriched Hyaluronic Acid in Facial Rejuvenation: A Systematic Review and Meta-Analysis.
topicHyaluronic Skin Aging Meta-Analysis
claimThis study aimed to evaluate the efficacy and safety of an injectable formulation combining hyaluronic acid (HA) and amino acids (AA) for facial rejuvenation in adults.
evidence level1
citationMosteirin M (2026)
sourceEfficacy and Safety of Amino Acid-Enriched Hyaluronic Acid in Facial Rejuvenation: A Systematic Review and Meta-Analysis.
topicHyaluronic Skin Aging Meta-Analysis
claimHowever, these treatments are associated with adverse effects, particularly with prolonged use [,,,].
evidence level1
citationLiang Yuxin (2026)
sourceImpact of Antioxidant-Rich Whole Foods or Supplements on Skin Health: A Systematic Review and Meta-Analysis of Preclinical and Clinical Studies
topicHyaluronic Skin Aging Meta-Analysis
claimThese properties may further improve skin barrier function, support collagen synthesis, increase hydration, and alleviate inflammation-associated skin conditions [,,,,,,,].
evidence level1
citationLiang Yuxin (2026)
sourceImpact of Antioxidant-Rich Whole Foods or Supplements on Skin Health: A Systematic Review and Meta-Analysis of Preclinical and Clinical Studies
topicHyaluronic Skin Aging Meta-Analysis
claimMost studies focus on isolated antioxidant supplements, leaving a gap in evidence regarding antioxidant-rich whole food interventions and comparative outcomes across various skin conditions.
evidence level1
citationLiang Yuxin (2026)
sourceImpact of Antioxidant-Rich Whole Foods or Supplements on Skin Health: A Systematic Review and Meta-Analysis of Preclinical and Clinical Studies
topicHyaluronic Skin Aging Meta-Analysis
claim1 2 As the most extensive organ of the human body, the skin functions as a vital interface against environmental insults, regulating temperature, preventing dehydration, and playing a crucial role in immune defense [].
evidence level1
citationLiang Yuxin (2026)
sourceImpact of Antioxidant-Rich Whole Foods or Supplements on Skin Health: A Systematic Review and Meta-Analysis of Preclinical and Clinical Studies