Structured evidence table for Hops Sleep Randomized Trial, generated from 2 reusable source documents in the Migaku knowledge base.
| topic | claim | evidence level | citation | source |
|---|---|---|---|---|
| Hops Sleep Randomized Trial | 1 2 3 4 5 6 7 8 9 10 Insomnia is a pervasive sleep disorder characterized by persistent difficulties in initiating or maintaining sleep or experiencing nonrestorative sleep despite adequate opportunity, leading to daytime impairment and reduced quality of life [,]. | 2 | Pakdee Naruwat (2026) | Integrative therapies for chronic insomnia: A randomized controlled trial of a traditional Thai Herbal Remedy and Cannabis sativa oil |
| Hops Sleep Randomized Trial | Pharmacological treatments using benzodiazepines, such as lorazepam, are standard for managing moderate to severe insomnia and anxiety-associated sleep disturbances owing to their efficacy and rapid onset of action [,]. | 2 | Pakdee Naruwat (2026) | Integrative therapies for chronic insomnia: A randomized controlled trial of a traditional Thai Herbal Remedy and Cannabis sativa oil |
| Hops Sleep Randomized Trial | The side effects and risk profile often limit the long-term utility of such medications and drive interest in safer alternatives []. | 2 | Pakdee Naruwat (2026) | Integrative therapies for chronic insomnia: A randomized controlled trial of a traditional Thai Herbal Remedy and Cannabis sativa oil |
| Hops Sleep Randomized Trial | Globally, approximately 10–30 % of adults report chronic insomnia symptoms, with even higher prevalence in older populations and those with comorbid conditions [,]. | 2 | Pakdee Naruwat (2026) | Integrative therapies for chronic insomnia: A randomized controlled trial of a traditional Thai Herbal Remedy and Cannabis sativa oil |
| Hops Sleep Randomized Trial | We also found a significant prolongation of the total duration in bed during the night (= 0.023,= 0.37) with an estimated increase in the duration in bed of 0.406 h (24.4 min) in the verum group compared to the placebo group (Table ). | 2 | Schicktanz Nathalie (2025) | Effects of a Valerian‐Hops Extract Combination (Ze 91019) on Sleep Duration and Daytime Cognitive and Psychological Parameters in Occasional Insomnia: A Randomized Controlled Feasibility Trial |
| Hops Sleep Randomized Trial | The exploratory analysis indicated that the valerian and hop‐fixed herbal combination (Ze 91019) significantly increased sleep duration compared to placebo, with an average increase of 21.7 min per night during the treatment period as measured by the Fitbit tracker. | 2 | Schicktanz Nathalie (2025) | Effects of a Valerian‐Hops Extract Combination (Ze 91019) on Sleep Duration and Daytime Cognitive and Psychological Parameters in Occasional Insomnia: A Randomized Controlled Feasibility Trial |
| Hops Sleep Randomized Trial | Moreover, Ze 91019 significantly increased the sleep duration of the shortest night in the treatment period by 48.7 minutes. | 2 | Schicktanz Nathalie (2025) | Effects of a Valerian‐Hops Extract Combination (Ze 91019) on Sleep Duration and Daytime Cognitive and Psychological Parameters in Occasional Insomnia: A Randomized Controlled Feasibility Trial |
| Hops Sleep Randomized Trial | 2006 2006 2004 2007 2002 Valeriana officinalis Humulus lupulus Sleep disturbances affect a significant portion of the adult general population, with about 30% reporting insomnia symptoms (Morin et al.). | 2 | Schicktanz Nathalie (2025) | Effects of a Valerian‐Hops Extract Combination (Ze 91019) on Sleep Duration and Daytime Cognitive and Psychological Parameters in Occasional Insomnia: A Randomized Controlled Feasibility Trial |
Source documents