evidence table

Holy Basil Anxiety Randomized Trial Evidence Table

Structured evidence table for Holy Basil Anxiety Randomized Trial, generated from 2 reusable source documents in the Migaku knowledge base.

topicclaimevidence levelcitationsource
Holy Basil Anxiety Randomized TrialResults At day 60, both VL-G-A57 and VL-G-E12 significantly reduced Perceived Stress Scale (PSS) scores compared to placebo (p Conclusion The study concluded that both VL-G-A57 and VL-G-E12 were associated with reductions in stress, fatigue, and anxiety while improving mood and sleep quality.2McKinney E (2026)Effects of multi-herb and ashwagandha root formulas on stress modulation: a randomized, double-blind, placebo-controlled clinical study.
Holy Basil Anxiety Randomized TrialBackground Chronic stress is detrimental to the maintenance of the main response system - the hypothalamic-pituitary-adrenal (HPA) axis.2McKinney E (2026)Effects of multi-herb and ashwagandha root formulas on stress modulation: a randomized, double-blind, placebo-controlled clinical study.
Holy Basil Anxiety Randomized TrialThe current study aimed to investigate the efficacy of two plant-based adaptogens, a formula containing Rhodiola, holy basil and Schisandra chinensis (VL-G-A57) and a full-spectrum ashwagandha (VL-G-E12), on stress and related symptoms in individuals with high stress.2McKinney E (2026)Effects of multi-herb and ashwagandha root formulas on stress modulation: a randomized, double-blind, placebo-controlled clinical study.
Holy Basil Anxiety Randomized TrialDepression can affect thoughts, mood, and physical health and can be associated with numerous symptoms such as low mood, fatigue, sadness, insomnia, anhedonia, and cognitive impairment symptoms (Li et al.; Schulz and Arora).2Talaei Mahva (2025)Basil ( Ocimum basilicum ) to Alleviate Anxiety in Patients With Major Depressive Disorder: A Randomized Placebo‐Controlled Clinical Trial
Holy Basil Anxiety Randomized TrialAnxiety disorders are the most common associated disorders in depressed patients.2Talaei Mahva (2025)Basil ( Ocimum basilicum ) to Alleviate Anxiety in Patients With Major Depressive Disorder: A Randomized Placebo‐Controlled Clinical Trial
Holy Basil Anxiety Randomized TrialAntidepressants are highly potent medications that can result in serious interactions with a wide range of substances (Marks).2Talaei Mahva (2025)Basil ( Ocimum basilicum ) to Alleviate Anxiety in Patients With Major Depressive Disorder: A Randomized Placebo‐Controlled Clinical Trial
Holy Basil Anxiety Randomized Trial2020 2020 2015 2018 2018 2016 2019 2010 Major depressive disorder (MDD), the most common mood disorder worldwide, is recognized as an increasing social burden and recently has been reported as a significant cause of mortality (Li et al.).2Talaei Mahva (2025)Basil ( Ocimum basilicum ) to Alleviate Anxiety in Patients With Major Depressive Disorder: A Randomized Placebo‐Controlled Clinical Trial
topicHoly Basil Anxiety Randomized Trial
claimResults At day 60, both VL-G-A57 and VL-G-E12 significantly reduced Perceived Stress Scale (PSS) scores compared to placebo (p Conclusion The study concluded that both VL-G-A57 and VL-G-E12 were associated with reductions in stress, fatigue, and anxiety while improving mood and sleep quality.
evidence level2
citationMcKinney E (2026)
sourceEffects of multi-herb and ashwagandha root formulas on stress modulation: a randomized, double-blind, placebo-controlled clinical study.
topicHoly Basil Anxiety Randomized Trial
claimBackground Chronic stress is detrimental to the maintenance of the main response system - the hypothalamic-pituitary-adrenal (HPA) axis.
evidence level2
citationMcKinney E (2026)
sourceEffects of multi-herb and ashwagandha root formulas on stress modulation: a randomized, double-blind, placebo-controlled clinical study.
topicHoly Basil Anxiety Randomized Trial
claimThe current study aimed to investigate the efficacy of two plant-based adaptogens, a formula containing Rhodiola, holy basil and Schisandra chinensis (VL-G-A57) and a full-spectrum ashwagandha (VL-G-E12), on stress and related symptoms in individuals with high stress.
evidence level2
citationMcKinney E (2026)
sourceEffects of multi-herb and ashwagandha root formulas on stress modulation: a randomized, double-blind, placebo-controlled clinical study.
topicHoly Basil Anxiety Randomized Trial
claimDepression can affect thoughts, mood, and physical health and can be associated with numerous symptoms such as low mood, fatigue, sadness, insomnia, anhedonia, and cognitive impairment symptoms (Li et al.; Schulz and Arora).
evidence level2
citationTalaei Mahva (2025)
sourceBasil ( Ocimum basilicum ) to Alleviate Anxiety in Patients With Major Depressive Disorder: A Randomized Placebo‐Controlled Clinical Trial
topicHoly Basil Anxiety Randomized Trial
claimAnxiety disorders are the most common associated disorders in depressed patients.
evidence level2
citationTalaei Mahva (2025)
sourceBasil ( Ocimum basilicum ) to Alleviate Anxiety in Patients With Major Depressive Disorder: A Randomized Placebo‐Controlled Clinical Trial
topicHoly Basil Anxiety Randomized Trial
claimAntidepressants are highly potent medications that can result in serious interactions with a wide range of substances (Marks).
evidence level2
citationTalaei Mahva (2025)
sourceBasil ( Ocimum basilicum ) to Alleviate Anxiety in Patients With Major Depressive Disorder: A Randomized Placebo‐Controlled Clinical Trial
topicHoly Basil Anxiety Randomized Trial
claim2020 2020 2015 2018 2018 2016 2019 2010 Major depressive disorder (MDD), the most common mood disorder worldwide, is recognized as an increasing social burden and recently has been reported as a significant cause of mortality (Li et al.).
evidence level2
citationTalaei Mahva (2025)
sourceBasil ( Ocimum basilicum ) to Alleviate Anxiety in Patients With Major Depressive Disorder: A Randomized Placebo‐Controlled Clinical Trial

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Source documents

  1. Effects of multi-herb and ashwagandha root formulas on stress modulation: a randomized, double-blind, placebo-controlled clinical study.
  2. Basil ( Ocimum basilicum ) to Alleviate Anxiety in Patients With Major Depressive Disorder: A Randomized Placebo‐Controlled Clinical Trial