Structured evidence table for Hmb Muscle Mass Meta-Analysis, generated from 2 reusable source documents in the Migaku knowledge base.
| topic | claim | evidence level | citation | source |
|---|---|---|---|---|
| Hmb Muscle Mass Meta-Analysis | The Cochrane ROB2 tool and GRADE framework were used to assess the risk of bias and evidence certainty. | 1 | Xie C (2026) | Combined resistance training and amino acid-based supplementation for sarcopenia in older adults: a systematic review and meta-analysis. |
| Hmb Muscle Mass Meta-Analysis | Conclusion Resistance training combined with amino acid supplementation may improve muscle strength and physical function in older adults with sarcopenia, although effects on muscle mass remain limited. | 1 | Xie C (2026) | Combined resistance training and amino acid-based supplementation for sarcopenia in older adults: a systematic review and meta-analysis. |
| Hmb Muscle Mass Meta-Analysis | Background and objective Resistance training is the cornerstone of sarcopenia management. | 1 | Xie C (2026) | Combined resistance training and amino acid-based supplementation for sarcopenia in older adults: a systematic review and meta-analysis. |
| Hmb Muscle Mass Meta-Analysis | However, whether combining it with amino acid-based supplementation, including essential amino acids, branched-chain amino acids, leucine, and derivatives such as HMB, provides additional benefits remains unclear. | 1 | Xie C (2026) | Combined resistance training and amino acid-based supplementation for sarcopenia in older adults: a systematic review and meta-analysis. |
| Hmb Muscle Mass Meta-Analysis | Methodological quality was assessed with the PEDro scale and risk of bias using Cochrane RoB 2. | 1 | García-Alonso A (2025) | The Role of HMB Supplementation in Enhancing the Effects of Resistance Training in Older Adults: A Systematic Review and Meta-Analysis on Muscle Quality, Body Composition, and Physical Function. |
| Hmb Muscle Mass Meta-Analysis | Five trials (50%) were rated at high risk of bias, limiting confidence in pooled estimates. | 1 | García-Alonso A (2025) | The Role of HMB Supplementation in Enhancing the Effects of Resistance Training in Older Adults: A Systematic Review and Meta-Analysis on Muscle Quality, Body Composition, and Physical Function. |
| Hmb Muscle Mass Meta-Analysis | Background/objectives Resistance training (RT) is a key strategy to counteract age-related declines in muscle strength and physical function. | 1 | García-Alonso A (2025) | The Role of HMB Supplementation in Enhancing the Effects of Resistance Training in Older Adults: A Systematic Review and Meta-Analysis on Muscle Quality, Body Composition, and Physical Function. |
| Hmb Muscle Mass Meta-Analysis | β-hydroxy-β-methylbutyrate (HMB) has been proposed as a complementary supplement to enhance these adaptations. | 1 | García-Alonso A (2025) | The Role of HMB Supplementation in Enhancing the Effects of Resistance Training in Older Adults: A Systematic Review and Meta-Analysis on Muscle Quality, Body Composition, and Physical Function. |
Source documents