Structured evidence table for Guarana Cognitive Performance Randomized Trial, generated from 3 reusable source documents in the Migaku knowledge base.
| topic | claim | evidence level | citation | source |
|---|---|---|---|---|
| Guarana Cognitive Performance Randomized Trial | Despite variation in population-based habitual consumption, moderate long-term caffeine intake (up to 400 mg/day) is not linked to adverse effects on male fertility, behavior, cancer risk, calcium balance, or cardiovascular health []. | 1 | Hack Brian (2023) | Effect of Guarana ( Paullinia cupana ) on Cognitive Performance: A Systematic Review and Meta-Analysis |
| Guarana Cognitive Performance Randomized Trial | These include a range of health outcomes associated with reductions in chronic fatigue in cancer patients [,], short-term weight and fat loss [], and potentially protective effects against metabolic disorders in elderly subjects in habitual consumers []. | 1 | Hack Brian (2023) | Effect of Guarana ( Paullinia cupana ) on Cognitive Performance: A Systematic Review and Meta-Analysis |
| Guarana Cognitive Performance Randomized Trial | However, a recent meta-analysis established that chronic supplementation of guarana did not reduce perceived fatigue in cancer patients and the quality of experimental evidence was rated as low []. | 1 | Hack Brian (2023) | Effect of Guarana ( Paullinia cupana ) on Cognitive Performance: A Systematic Review and Meta-Analysis |
| Guarana Cognitive Performance Randomized Trial | 1 2 3 Nutritional ergogenic aids may increase human performance by different mechanisms. | 1 | Hack Brian (2023) | Effect of Guarana ( Paullinia cupana ) on Cognitive Performance: A Systematic Review and Meta-Analysis |
| Guarana Cognitive Performance Randomized Trial | Guarana significantly improved TMT-A performance compared with placebo ( p = 0.005, η 2 p = 0.05), whereas no significant differences were observed for TMT-B ( p = 0.08, η 2 p = 0.02). | 4 | Rekik S (2026) | Acute Effects of Guarana (<i>Paullinia cupana</i>) Supplementation on Cognitive Performance, Technical Skills, and Physiological Responses in Amateur Soccer Players. |
| Guarana Cognitive Performance Randomized Trial | A significant Group × Time interaction was found for total LSPT performance time ( p = 0.01, η 2 p = 0.06), driven by a significant technical performance optimization at pre-exercise ( p p > 0.05). | 4 | Rekik S (2026) | Acute Effects of Guarana (<i>Paullinia cupana</i>) Supplementation on Cognitive Performance, Technical Skills, and Physiological Responses in Amateur Soccer Players. |
| Guarana Cognitive Performance Randomized Trial | Concurrently, it significantly reduced perceived mental exertion ( p p p > 0.05). | 4 | Rekik S (2026) | Acute Effects of Guarana (<i>Paullinia cupana</i>) Supplementation on Cognitive Performance, Technical Skills, and Physiological Responses in Amateur Soccer Players. |
| Guarana Cognitive Performance Randomized Trial | This study investigated the acute effects of guarana supplementation on cognitive, technical, physiological, and psychological responses in soccer players prior to, during, and following high-intensity 4 vs. | 4 | Rekik S (2026) | Acute Effects of Guarana (<i>Paullinia cupana</i>) Supplementation on Cognitive Performance, Technical Skills, and Physiological Responses in Amateur Soccer Players. |
| Guarana Cognitive Performance Randomized Trial | This narrative review synthesizes evidence on naturally derived compounds that influence these pathways, including guayusa, guarana, Alpinia galanga , theobromine, L-citrulline, beetroot extract, cordyceps, and niacin, as well as natural sweeteners such as monk fruit and stevia. | 4 | Panda R (2026) | Synergistic Actions of Natural Compounds for Enhancing Cognitive and Physical Performance: A Narrative Review. |
| Guarana Cognitive Performance Randomized Trial | Evidence suggests that these agents may support cognitive performance, oxygen efficiency, vascular perfusion, and cellular energy capacity through mechanisms distinct from those of traditional energy drinks. | 4 | Panda R (2026) | Synergistic Actions of Natural Compounds for Enhancing Cognitive and Physical Performance: A Narrative Review. |
| Guarana Cognitive Performance Randomized Trial | Energy drinks are widely consumed for cognitive and physical enhancement, yet most commercial formulations rely on a narrow mechanism: rapid stimulation from synthetic caffeine combined with artificial sweeteners. | 4 | Panda R (2026) | Synergistic Actions of Natural Compounds for Enhancing Cognitive and Physical Performance: A Narrative Review. |
| Guarana Cognitive Performance Randomized Trial | This stimulant-centric strategy overlooks the multidimensional physiology underlying sustained human energy, which emerges from interactions among neurocognitive activation, nitric oxide-mediated vascular function, mitochondrial ATP production, and metabolic homeostasis. | 4 | Panda R (2026) | Synergistic Actions of Natural Compounds for Enhancing Cognitive and Physical Performance: A Narrative Review. |
Source documents