topicGrape Seed Skin Aging Meta-Analysis
claimRather than presenting a catalogue of individual findings, this review emphasizes recurrent functional trends and coordinated proteome remodeling, with the aim of identifying robust protein markers associated with stress tolerance, developmental processes, and enological traits.
evidence level3
citationTomaz Ivana (2026)
sourceDecoding the Functional Proteome of Vitis : Past, Present, and Future
topicGrape Seed Skin Aging Meta-Analysis
claim20 21 22 23 24 25 Vitis vinifera Muscadinia In the 1980s, analytical resolution improved further, allowing soluble proteins to be resolved into dozens of fractions [,,], and enabling comparative analyses betweenandspecies based on molecular weight and isoelectric point differences [].
evidence level3
citationTomaz Ivana (2026)
sourceDecoding the Functional Proteome of Vitis : Past, Present, and Future
topicGrape Seed Skin Aging Meta-Analysis
claimThese proteins are primarily associated with cell wall modification, lignification, and constitutive defense, indicating that structural and protective processes are closely linked to leaf metabolism.
evidence level3
citationTomaz Ivana (2026)
sourceDecoding the Functional Proteome of Vitis : Past, Present, and Future
topicGrape Seed Skin Aging Meta-Analysis
claimVitis Vitis Vitis vinifera 1 2 3 The genusis among the most economically important plant taxa.
evidence level3
citationTomaz Ivana (2026)
sourceDecoding the Functional Proteome of Vitis : Past, Present, and Future
topicGrape Seed Skin Aging Meta-Analysis
claimThe oldest biomolecular archaeological evidence for grape wine and viniculture in the South Caucasus region dates to the early Neolithic period (ca.
evidence level3
citationMittova Valentina (2026)
sourceGeorgian Grapes and Wines as a Source of Phenolic Compounds: Composition, Antioxidant Activity, and Traditional Winemaking †
topicGrape Seed Skin Aging Meta-Analysis
claimFinally, the “dablari” method creates typical vineyards found in commercial areas, grapevines grown close to the ground, without the use of a tree for support, with this method being used mainly in western and eastern Georgia [].
evidence level3
citationMittova Valentina (2026)
sourceGeorgian Grapes and Wines as a Source of Phenolic Compounds: Composition, Antioxidant Activity, and Traditional Winemaking †
topicGrape Seed Skin Aging Meta-Analysis
claimPolyphenolic compounds in grapes are mainly found in the skin (28–35%), seeds (60–70%), and stems, while their content in the pulp is much lower and does not exceed 10% [].
evidence level3
citationMittova Valentina (2026)
sourceGeorgian Grapes and Wines as a Source of Phenolic Compounds: Composition, Antioxidant Activity, and Traditional Winemaking †
topicGrape Seed Skin Aging Meta-Analysis
claim1 2 3 4 5 6 7 8 9 7 10 11 The antioxidant properties of natural products have garnered significant attention in recent years, since antioxidants have various pharmacological properties such as cardioprotective, neuroprotective, anti-inflammatory, anticancer, and anti-aging activities [,].
evidence level3
citationMittova Valentina (2026)
sourceGeorgian Grapes and Wines as a Source of Phenolic Compounds: Composition, Antioxidant Activity, and Traditional Winemaking †