Structured evidence table for Grape Seed Extract Cholesterol Meta-Analysis, generated from 2 reusable source documents in the Migaku knowledge base.
| topic | claim | evidence level | citation | source |
|---|---|---|---|---|
| Grape Seed Extract Cholesterol Meta-Analysis | Demographics such as aging, ethnicity (particularly, Asian, American, Pacific Islander, African American, and Hispanic/Latino), and historical antecedents are associated with health-related issues []. | 3 | Javaid Nazish (2026) | Sea Buckthorn ( Hippophae rhamnoides L.): Nutritional Significance, Phytochemistry, Molecular Mechanisms, Therapeutic Potential, and Emerging Applications in Food Systems |
| Grape Seed Extract Cholesterol Meta-Analysis | Bioactive substances like flavonoids and palmitoleic acid found in SB enhance biological activity by modulating signaling pathways of AMPK and PI3K/Akt []. | 3 | Javaid Nazish (2026) | Sea Buckthorn ( Hippophae rhamnoides L.): Nutritional Significance, Phytochemistry, Molecular Mechanisms, Therapeutic Potential, and Emerging Applications in Food Systems |
| Grape Seed Extract Cholesterol Meta-Analysis | Preclinical evidence indicates that SB may exhibit immune-modulating and anti-oxidative properties [], cardio-protective and anti-atherogenic effects [,], as well as antiviral and antibacterial activities []. | 3 | Javaid Nazish (2026) | Sea Buckthorn ( Hippophae rhamnoides L.): Nutritional Significance, Phytochemistry, Molecular Mechanisms, Therapeutic Potential, and Emerging Applications in Food Systems |
| Grape Seed Extract Cholesterol Meta-Analysis | 1 2 3 4 5 The sedentary lifestyle, poor diet (high in refined carbohydrates, sugary beverages, saturated/trans fats), existential distress/anxiety, sleep deprivation, and smoking all contribute to several health risks []. | 3 | Javaid Nazish (2026) | Sea Buckthorn ( Hippophae rhamnoides L.): Nutritional Significance, Phytochemistry, Molecular Mechanisms, Therapeutic Potential, and Emerging Applications in Food Systems |
| Grape Seed Extract Cholesterol Meta-Analysis | 6 7 Despite advances in surgical techniques, chemotherapy, immunotherapy, and radiotherapy, standard CRC treatments often result in adverse effects such as mucositis, nausea, and anorexia []. | 3 | Verdi Anderson Matheus Oliveira Haas (2025) | Nutraceutical Interception of Cachexia: Grape-Derived Compounds as Pathophysiological Network Modulators |
| Grape Seed Extract Cholesterol Meta-Analysis | When compounded by tumor-driven metabolic dysregulation, these factors contribute to a catabolic environment that predisposes patients to cancer-associated cachexia—a multifactorial syndrome affecting up to 80% of those with gastrointestinal malignancies []. | 3 | Verdi Anderson Matheus Oliveira Haas (2025) | Nutraceutical Interception of Cachexia: Grape-Derived Compounds as Pathophysiological Network Modulators |
| Grape Seed Extract Cholesterol Meta-Analysis | Its pathogenesis involves more than reduced caloric intake; it encompasses profound metabolic alterations, frequently including insulin resistance, accelerated proteolysis, and increased resting energy expenditure []. | 3 | Verdi Anderson Matheus Oliveira Haas (2025) | Nutraceutical Interception of Cachexia: Grape-Derived Compounds as Pathophysiological Network Modulators |
| Grape Seed Extract Cholesterol Meta-Analysis | 1 2 3 4 5 Colorectal cancer (CRC) remains one of the most prevalent malignancies worldwide, ranking third in incidence and second in cancer-related mortality, according to recent GLOBOCAN estimates []. | 3 | Verdi Anderson Matheus Oliveira Haas (2025) | Nutraceutical Interception of Cachexia: Grape-Derived Compounds as Pathophysiological Network Modulators |
Source documents