evidence table

Glycine Muscle Recovery Randomized Trial Evidence Table

Structured evidence table for Glycine Muscle Recovery Randomized Trial, generated from 1 reusable source document in the Migaku knowledge base.

topicclaimevidence levelcitationsource
Glycine Muscle Recovery Randomized Trial1 Aging is characterized by progressive physiological decline, including loss of skeletal muscle mass and function (Sarcopenia), reduced mitochondrial efficiency, and increased oxidative stress, all of which contribute to frailty and diminished quality of life in older adults ().3Wang Xiaolan (2026)Glycine and N-acetylcysteine supplementation, with or without exercise, in brain health and functional aging: implications for sarcopenia and frailty in older adults
Glycine Muscle Recovery Randomized Trial1 2 3 4 5 By the age of 70, individuals may experience a 25%−30% reduction in muscle mass, which is strongly associated with impaired mobility, falls, and loss of independence ().3Wang Xiaolan (2026)Glycine and N-acetylcysteine supplementation, with or without exercise, in brain health and functional aging: implications for sarcopenia and frailty in older adults
Glycine Muscle Recovery Randomized TrialLow circulating glycine levels have been associated with insulin resistance, obesity, and higher cardiometabolic risk (,).3Wang Xiaolan (2026)Glycine and N-acetylcysteine supplementation, with or without exercise, in brain health and functional aging: implications for sarcopenia and frailty in older adults
Glycine Muscle Recovery Randomized TrialIn this review, the term “older adults” generally refers to individuals aged ≥60 or ≥65 years, consistent with definitions used by the World Health Organization and most geriatric clinical trials.3Wang Xiaolan (2026)Glycine and N-acetylcysteine supplementation, with or without exercise, in brain health and functional aging: implications for sarcopenia and frailty in older adults
topicGlycine Muscle Recovery Randomized Trial
claim1 Aging is characterized by progressive physiological decline, including loss of skeletal muscle mass and function (Sarcopenia), reduced mitochondrial efficiency, and increased oxidative stress, all of which contribute to frailty and diminished quality of life in older adults ().
evidence level3
citationWang Xiaolan (2026)
sourceGlycine and N-acetylcysteine supplementation, with or without exercise, in brain health and functional aging: implications for sarcopenia and frailty in older adults
topicGlycine Muscle Recovery Randomized Trial
claim1 2 3 4 5 By the age of 70, individuals may experience a 25%−30% reduction in muscle mass, which is strongly associated with impaired mobility, falls, and loss of independence ().
evidence level3
citationWang Xiaolan (2026)
sourceGlycine and N-acetylcysteine supplementation, with or without exercise, in brain health and functional aging: implications for sarcopenia and frailty in older adults
topicGlycine Muscle Recovery Randomized Trial
claimLow circulating glycine levels have been associated with insulin resistance, obesity, and higher cardiometabolic risk (,).
evidence level3
citationWang Xiaolan (2026)
sourceGlycine and N-acetylcysteine supplementation, with or without exercise, in brain health and functional aging: implications for sarcopenia and frailty in older adults
topicGlycine Muscle Recovery Randomized Trial
claimIn this review, the term “older adults” generally refers to individuals aged ≥60 or ≥65 years, consistent with definitions used by the World Health Organization and most geriatric clinical trials.
evidence level3
citationWang Xiaolan (2026)
sourceGlycine and N-acetylcysteine supplementation, with or without exercise, in brain health and functional aging: implications for sarcopenia and frailty in older adults

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Source documents

  1. Glycine and N-acetylcysteine supplementation, with or without exercise, in brain health and functional aging: implications for sarcopenia and frailty in older adults