evidence table

Glycerol Exercise Hydration Randomized Trial Evidence Table

Structured evidence table for Glycerol Exercise Hydration Randomized Trial, generated from 2 reusable source documents in the Migaku knowledge base.

topicclaimevidence levelcitationsource
Glycerol Exercise Hydration Randomized TrialBackground Endurance athletes experience significant water loss during exercise, which can impair performance and increase the risk of dehydration.2Herrera-Amante CA (2025)Effects of glycerol hyperhidration on the running economy of long-distance runners: a randomized crossover clinical trial.
Glycerol Exercise Hydration Randomized TrialResults Glycerol supplementation significantly improved running economy, reducing CCU ( p = 0.025, d = 0.43), OCU ( p = 0.011, r = 0.46), HR ( p = 0.029, d = 0.42), and RPE ( p = 0.003, d = 0.60).2Herrera-Amante CA (2025)Effects of glycerol hyperhidration on the running economy of long-distance runners: a randomized crossover clinical trial.
Glycerol Exercise Hydration Randomized TrialAlthough BT showed a slight decrease ( p = 0.053, d = 0.37), it did not reach statistical significance, suggesting a trend toward improved thermoregulation.2Herrera-Amante CA (2025)Effects of glycerol hyperhidration on the running economy of long-distance runners: a randomized crossover clinical trial.
Glycerol Exercise Hydration Randomized TrialGlycerol hyperhydration has been explored as a strategy to enhance pre-exercise hydration, particularly when fluid intake opportunities are limited.2Herrera-Amante CA (2025)Effects of glycerol hyperhidration on the running economy of long-distance runners: a randomized crossover clinical trial.
Glycerol Exercise Hydration Randomized TrialCompared to G and CON, blood pH and blood bicarbonate concentration was significantly higher with G + SB and SB from 60-180 min (p Conclusions Fluid retention improved in G, SB and G + SB compared to CON, although there were no additive effects with G + SB compared to SB or G.4Patrick B (2026)Combined glycerol and sodium bicarbonate elicits improvements in fluid retention and blood buffering capacity.
Glycerol Exercise Hydration Randomized TrialIntroduction Background: It is unclear whether hyperhydration induced via glycerol, sodium bicarbonate or a combination of the two is most effective.4Patrick B (2026)Combined glycerol and sodium bicarbonate elicits improvements in fluid retention and blood buffering capacity.
Glycerol Exercise Hydration Randomized TrialAim: This study evaluated the effects of glycerol-, sodium bicarbonate-, and glycerol + sodium bicarbonate-induced hyperhydration on measures of fluid retention, blood buffering capacity, and gastrointestinal symptoms at rest, in comparison to a fluid-only control.4Patrick B (2026)Combined glycerol and sodium bicarbonate elicits improvements in fluid retention and blood buffering capacity.
topicGlycerol Exercise Hydration Randomized Trial
claimBackground Endurance athletes experience significant water loss during exercise, which can impair performance and increase the risk of dehydration.
evidence level2
citationHerrera-Amante CA (2025)
sourceEffects of glycerol hyperhidration on the running economy of long-distance runners: a randomized crossover clinical trial.
topicGlycerol Exercise Hydration Randomized Trial
claimResults Glycerol supplementation significantly improved running economy, reducing CCU ( p = 0.025, d = 0.43), OCU ( p = 0.011, r = 0.46), HR ( p = 0.029, d = 0.42), and RPE ( p = 0.003, d = 0.60).
evidence level2
citationHerrera-Amante CA (2025)
sourceEffects of glycerol hyperhidration on the running economy of long-distance runners: a randomized crossover clinical trial.
topicGlycerol Exercise Hydration Randomized Trial
claimAlthough BT showed a slight decrease ( p = 0.053, d = 0.37), it did not reach statistical significance, suggesting a trend toward improved thermoregulation.
evidence level2
citationHerrera-Amante CA (2025)
sourceEffects of glycerol hyperhidration on the running economy of long-distance runners: a randomized crossover clinical trial.
topicGlycerol Exercise Hydration Randomized Trial
claimGlycerol hyperhydration has been explored as a strategy to enhance pre-exercise hydration, particularly when fluid intake opportunities are limited.
evidence level2
citationHerrera-Amante CA (2025)
sourceEffects of glycerol hyperhidration on the running economy of long-distance runners: a randomized crossover clinical trial.
topicGlycerol Exercise Hydration Randomized Trial
claimCompared to G and CON, blood pH and blood bicarbonate concentration was significantly higher with G + SB and SB from 60-180 min (p Conclusions Fluid retention improved in G, SB and G + SB compared to CON, although there were no additive effects with G + SB compared to SB or G.
evidence level4
citationPatrick B (2026)
sourceCombined glycerol and sodium bicarbonate elicits improvements in fluid retention and blood buffering capacity.
topicGlycerol Exercise Hydration Randomized Trial
claimIntroduction Background: It is unclear whether hyperhydration induced via glycerol, sodium bicarbonate or a combination of the two is most effective.
evidence level4
citationPatrick B (2026)
sourceCombined glycerol and sodium bicarbonate elicits improvements in fluid retention and blood buffering capacity.
topicGlycerol Exercise Hydration Randomized Trial
claimAim: This study evaluated the effects of glycerol-, sodium bicarbonate-, and glycerol + sodium bicarbonate-induced hyperhydration on measures of fluid retention, blood buffering capacity, and gastrointestinal symptoms at rest, in comparison to a fluid-only control.
evidence level4
citationPatrick B (2026)
sourceCombined glycerol and sodium bicarbonate elicits improvements in fluid retention and blood buffering capacity.

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Source documents

  1. Effects of glycerol hyperhidration on the running economy of long-distance runners: a randomized crossover clinical trial.
  2. Combined glycerol and sodium bicarbonate elicits improvements in fluid retention and blood buffering capacity.