Glucosamine Osteoarthritis Meta-Analysis Evidence Table

Structured evidence table for Glucosamine Osteoarthritis Meta-Analysis, generated from 2 reusable source documents in the Migaku knowledge base.

topicclaimevidence levelcitationsource
Glucosamine Osteoarthritis Meta-AnalysisThis review suggests that EAS may be an effective and relatively safe adjunctive option for KOA; however, the certainty of the evidence is low due to substantial heterogeneity and potential biases.1Yang G (2025)The efficacy and safety of electrical acupoint stimulation (EAS) for knee osteoarthritis (KOA): A GRADE-assessed systematic review, meta-analysis and trial sequential analysis.
Glucosamine Osteoarthritis Meta-AnalysisElectrical acupoint stimulation (EAS) is proposed as a potentially beneficial treatment for patients suffering from knee osteoarthritis (KOA).1Yang G (2025)The efficacy and safety of electrical acupoint stimulation (EAS) for knee osteoarthritis (KOA): A GRADE-assessed systematic review, meta-analysis and trial sequential analysis.
Glucosamine Osteoarthritis Meta-AnalysisThis systematic review and meta-analysis aims to assess the assess the effectiveness and safety of EAS for KOA.1Yang G (2025)The efficacy and safety of electrical acupoint stimulation (EAS) for knee osteoarthritis (KOA): A GRADE-assessed systematic review, meta-analysis and trial sequential analysis.
Glucosamine Osteoarthritis Meta-Analysis, , d d N Figure Chondroitin sulfate (CS) is an anionic, sulfated glycosaminoglycan found in various connective tissues, including cartilage, bone, ligaments, tendons, and skin.3Silva Vitor Alfredo de Santana (2025)Impact of Symptomatic Slow-Acting Drugs on Inflammatory Pathways in Osteoarthritis: Therapeutic Advances and Future Challenges
Glucosamine Osteoarthritis Meta-AnalysisIn terrestrial animals, it is predominantly found as monosulfated disaccharides at the 4-O or 6-O positions of GalNAc (CS-A and CS-C, respectively), along with a small percentage of nonsulfated disaccharides (CS-0).3Silva Vitor Alfredo de Santana (2025)Impact of Symptomatic Slow-Acting Drugs on Inflammatory Pathways in Osteoarthritis: Therapeutic Advances and Future Challenges
Glucosamine Osteoarthritis Meta-AnalysisWhile foundational and pioneering studies are acknowledged, particular emphasis is placed on the most recent evidence to capture the current state of knowledge, clarify ongoing controversies, and highlight the latest therapeutic advances.3Silva Vitor Alfredo de Santana (2025)Impact of Symptomatic Slow-Acting Drugs on Inflammatory Pathways in Osteoarthritis: Therapeutic Advances and Future Challenges
Glucosamine Osteoarthritis Meta-AnalysisOsteoarthritis (OA) is a highly prevalent musculoskeletal rheumatic disorder that significantly impacts individual health, healthcare systems, and overall socioeconomic costs.OA remains a substantial global health burden: in 2020, an estimated 595 million people (≈7.6% of the global population) had OA, representing a 132.2% increase in cases since 1990.3Silva Vitor Alfredo de Santana (2025)Impact of Symptomatic Slow-Acting Drugs on Inflammatory Pathways in Osteoarthritis: Therapeutic Advances and Future Challenges

Source documents

  1. The efficacy and safety of electrical acupoint stimulation (EAS) for knee osteoarthritis (KOA): A GRADE-assessed systematic review, meta-analysis and trial sequential analysis.
  2. Impact of Symptomatic Slow-Acting Drugs on Inflammatory Pathways in Osteoarthritis: Therapeutic Advances and Future Challenges