Structured evidence table for Glucosamine Mobility Meta-Analysis, generated from 2 reusable source documents in the Migaku knowledge base.
| topic | claim | evidence level | citation | source |
|---|---|---|---|---|
| Glucosamine Mobility Meta-Analysis | To ensure a robust synthesis of evidence, we conducted a systematic search of PubMed, Embase, and Web of Science (2020-2025) for high-quality clinical trials, meta-analyses, and guidelines. | 4 | Wang H (2026) | Evolving Strategies for Knee Osteoarthritis: A Narrative Review of Integrated Rehabilitation, Pharmacologic, and Joint-Preserving Interventions. |
| Glucosamine Mobility Meta-Analysis | This narrative review evaluates the clinical transition from reactive, surgery-centric models to a proactive, integrated framework to mitigate the profound socioeconomic burden and functional decline associated with the disease. | 4 | Wang H (2026) | Evolving Strategies for Knee Osteoarthritis: A Narrative Review of Integrated Rehabilitation, Pharmacologic, and Joint-Preserving Interventions. |
| Glucosamine Mobility Meta-Analysis | We synthesized evidence across non-pharmacological rehabilitation, pharmacotherapy, and advanced joint-preserving surgeries, emphasizing optimal intervention windows and stage-specific mechanobiological requirements. | 4 | Wang H (2026) | Evolving Strategies for Knee Osteoarthritis: A Narrative Review of Integrated Rehabilitation, Pharmacologic, and Joint-Preserving Interventions. |
| Glucosamine Mobility Meta-Analysis | Knee osteoarthritis (KOA) is a primary driver of global disability, currently affecting over 365 million adults, with projections suggesting a 74.9% increase by 2050. | 4 | Wang H (2026) | Evolving Strategies for Knee Osteoarthritis: A Narrative Review of Integrated Rehabilitation, Pharmacologic, and Joint-Preserving Interventions. |
| Glucosamine Mobility Meta-Analysis | It causes chronic pain, reduced mobility, and disability, affecting 607 million individuals worldwide, with nearly 46.6 million new cases annually []. | 4 | Muacevic Alexander (2026) | Evidence-Based Use of Undenatured Type II Collagen in the Management of Osteoarthritis in the Indian Subcontinent and Southeast Asia: A Narrative Review and an Expert Opinion |
| Glucosamine Mobility Meta-Analysis | 11 12 13 14 15 11 15 HLA-DRB1 HLA-DQB1 Genetic polymorphisms in sterol regulatory element-binding protein 2 (rs2228314) [], interleukin-6 (rs1800795) [], and resistin (RETN) [] in Indian and Pakistani cohorts and growth differentiation factor 5 (rs143383) [],, andin Thai populations [] are linked to OA risk. | 4 | Muacevic Alexander (2026) | Evidence-Based Use of Undenatured Type II Collagen in the Management of Osteoarthritis in the Indian Subcontinent and Southeast Asia: A Narrative Review and an Expert Opinion |
| Glucosamine Mobility Meta-Analysis | Need for expert opinion Despite growing clinical and mechanistic evidence for collagen supplementation in OA, several gaps and challenges remain in translating this knowledge into clinical practice, especially in the Indian subcontinent and Southeast Asia. | 4 | Muacevic Alexander (2026) | Evidence-Based Use of Undenatured Type II Collagen in the Management of Osteoarthritis in the Indian Subcontinent and Southeast Asia: A Narrative Review and an Expert Opinion |
| Glucosamine Mobility Meta-Analysis | 1 2 3 4 6 7 8 9 10 1 Osteoarthritis (OA) is the most prevalent degenerative joint disease globally and the second most common rheumatologic condition []. | 4 | Muacevic Alexander (2026) | Evidence-Based Use of Undenatured Type II Collagen in the Management of Osteoarthritis in the Indian Subcontinent and Southeast Asia: A Narrative Review and an Expert Opinion |
Source documents