evidence table
Glucosamine Knee Osteoarthritis Meta-Analysis Evidence Table
Structured evidence table for Glucosamine Knee Osteoarthritis Meta-Analysis, generated from 2 reusable source documents in the Migaku knowledge base.
| topic | claim | evidence level | citation | source |
|---|---|---|---|---|
| Glucosamine Knee Osteoarthritis Meta-Analysis | Background Osteoarthritis is a common joint disease, especially among individuals aged 50 and older, leading to symptoms such as pain, stiffness, and functional limitations, particularly in weight-bearing joints like the knees. | 2 | Čeh T (2026) | Complementary effect of a combined exercise and dietary supplement intervention in individuals with knee osteoarthritis: study protocol for a randomized, double-blind, placebo-controlled trial. |
| Glucosamine Knee Osteoarthritis Meta-Analysis | Knee osteoarthritis (KOA) is increasingly prevalent, making effective treatment strategies critical. | 2 | Čeh T (2026) | Complementary effect of a combined exercise and dietary supplement intervention in individuals with knee osteoarthritis: study protocol for a randomized, double-blind, placebo-controlled trial. |
| Glucosamine Knee Osteoarthritis Meta-Analysis | , , d d N Figure Chondroitin sulfate (CS) is an anionic, sulfated glycosaminoglycan found in various connective tissues, including cartilage, bone, ligaments, tendons, and skin. | 3 | Silva Vitor Alfredo de Santana (2025) | Impact of Symptomatic Slow-Acting Drugs on Inflammatory Pathways in Osteoarthritis: Therapeutic Advances and Future Challenges |
| Glucosamine Knee Osteoarthritis Meta-Analysis | In terrestrial animals, it is predominantly found as monosulfated disaccharides at the 4-O or 6-O positions of GalNAc (CS-A and CS-C, respectively), along with a small percentage of nonsulfated disaccharides (CS-0). | 3 | Silva Vitor Alfredo de Santana (2025) | Impact of Symptomatic Slow-Acting Drugs on Inflammatory Pathways in Osteoarthritis: Therapeutic Advances and Future Challenges |
| Glucosamine Knee Osteoarthritis Meta-Analysis | While foundational and pioneering studies are acknowledged, particular emphasis is placed on the most recent evidence to capture the current state of knowledge, clarify ongoing controversies, and highlight the latest therapeutic advances. | 3 | Silva Vitor Alfredo de Santana (2025) | Impact of Symptomatic Slow-Acting Drugs on Inflammatory Pathways in Osteoarthritis: Therapeutic Advances and Future Challenges |
| Glucosamine Knee Osteoarthritis Meta-Analysis | Osteoarthritis (OA) is a highly prevalent musculoskeletal rheumatic disorder that significantly impacts individual health, healthcare systems, and overall socioeconomic costs.OA remains a substantial global health burden: in 2020, an estimated 595 million people (≈7.6% of the global population) had OA, representing a 132.2% increase in cases since 1990. | 3 | Silva Vitor Alfredo de Santana (2025) | Impact of Symptomatic Slow-Acting Drugs on Inflammatory Pathways in Osteoarthritis: Therapeutic Advances and Future Challenges |
Source documents
- Complementary effect of a combined exercise and dietary supplement intervention in individuals with knee osteoarthritis: study protocol for a randomized, double-blind, placebo-controlled trial.
- Impact of Symptomatic Slow-Acting Drugs on Inflammatory Pathways in Osteoarthritis: Therapeutic Advances and Future Challenges